Evidence map›Paper›PMID 37213552›Full record

ArticleData in brief2023

A dataset of multi-contrast unbiased average MRI templates of a Parkinson's disease population.

Victoria Madge, Vladimir S Fonov, Yiming Xiao, Lucy Zou, Courtney Jackson, Ronald B Postuma, Alain Dagher, Edward A Fon, D Louis Collins

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Baseline [NPJ Parkinson's disease · 2025
    Article
  2. Selective Effects of Substantia Nigra and Locus Coeruleus Degeneration on Cognition in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Victoria MadgeMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Vladimir S FonovMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Yiming XiaoConcordia University, Montreal, QC, Canada.
Lucy ZouMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Courtney JacksonMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Ronald B PostumaMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Alain DagherMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Edward A FonMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
D Louis CollinsMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Montreal Neurological Institute and Hospital · CAConcordia University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a complex neurodegenerative disorder affecting regions such as the substantia nigra (SN), red nucleus (RN) and locus coeruleus (LC). Processing MRI data from patients with PD requires anatomical structural references for spatial normalization and structural segmentation. Extending our previous work, we present multi-contrast unbiased MRI templates using nine 3T MRI modalities: T1w, T2*w, T1-T2* fusion, R2*, T2w, PDw, fluid-attenuated inversion recovery (FLAIR), susceptibility-weighted imaging, and neuromelanin-sensitive MRI (NM). One mm isotropic voxel size templates were created, along with 0.5 mm isotropic whole brain templates and 0.3 mm isotropic templates of the midbrain. All templates were created from 126 PD patients (44 female; ages=40-87), and 17 healthy controls (13 female; ages=39-84), except the NM template, which was created from 85 PD patients and 13 controls, respectively. The dataset is available on the NIST MNI Repository via the following link: http://nist.mni.mcgill.ca/multi-contrast-pd126-and-ctrl17-templates/. The data is also available on NITRC at the following link: https://www.nitrc.org/projects/pd126/.

Indexed as

Magnetic resonance imaging (MRI)MidbrainNeuromelanin-sensitive imagingParkinson's diseaseSubstantia nigraSusceptibility-weighted imaging (SWI)Template

Identifiers

PMID37213552
PMCPMC10197003
OpenAlexW4365147931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.