Evidence map›Paper›PMID 37213403›Full record

Trial reportWorld journal of gastroenterology2023

Fecal microbiota transplantation for the maintenance of remission in patients with ulcerative colitis: A randomized controlled trial.

Perttu Lahtinen, Jonna Jalanka, Eero Mattila, Jyrki Tillonen, Paula Bergman, Reetta Satokari, Perttu Arkkila

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 6 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 6 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  15. Fecal Microbiota Transplantation Attenuated Inflammation Through TGF-β1/Smad Signaling Pathway in Caco-2 and RAW264.7 Cells.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
  16. Review
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  19. OralFrontiers in cellular and infection microbiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Perttu LahtinenDepartment of Gastroenterology, Päijät-Häme Central Hospital, Lahti 15610, Finland.
Jonna JalankaHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland.
Eero MattilaDepartment of Infectious Diseases, Helsinki University Hospital, Helsinki 00029, Uusimaa, Finland.
Jyrki TillonenDepartment of Gastroenterology, Päijät-Häme Central Hospital, Lahti 15610, Finland.
Paula BergmanDepartment of Bioinformatics, Helsinki University Hospital, Helsinki 00014, Finland.
Reetta SatokariHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland.
Perttu ArkkilaDepartment of Gastroenterology, University Helsinki, Center Hospital, Helsinki 00029, Uusimaa, Finland.
University of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFecal microbial transplantation (FMT) is a promising new method for treating active ulcerative colitis (UC), but knowledge regarding FMT for quiescent UC is scarce.

aimTo investigate FMT for the maintenance of remission in UC patients.

methodsForty-eight UC patients were randomized to receive a single-dose FMT or autologous transplant

resultsThe main endpoint was achieved by 13 out of 24 (54%) patients in the FMT group and by 10 out of 24 (41%) patients in the placebo group (log-rank test,

conclusionThere were no differences in the number of relapses between the study groups at the 12-mo follow-up. Thus, our results do not support the use of a single-dose FMT for the maintenance of remission in UC.

Indexed as

Colitis, UlcerativeFecal Microbiota TransplantationFecesHumansLeukocyte L1 Antigen ComplexQuality of LifeRemission InductionLeukocyte L1 Antigen ComplexFecal calprotectinFecal microbial transplantationInflammatory bowel diseaseMaintenance of remissionQuality of lifeUlcerative colitis

Identifiers

PMID37213403
PMCPMC10198050
OpenAlexW4372341366

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.