Evidence map›Paper›PMID 37213392›Full record

ArticleFrontiers in psychology2023

Relationship between depression, anxiety, stress, and SARS-CoV-2 infection: a longitudinal study.

Dietmar Ausserhofer, Angelika Mahlknecht, Adolf Engl, Giuliano Piccoliori, Gernot Pfitscher, Philipp Silbernagl, Francesca Giacomoni, Roger Pycha, Stefano Lombardo, Timon Gärtner and 4 more

Abstract read
In one paragraph

Article in Frontiers in psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Altered brain function and structure pre- and post- COVID-19 infection: a longitudinal study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dietmar AusserhoferInstitute of General Practice and Public Health, College of Health Care-Professions Claudiana, Bolzano-Bozen, Italy.
Angelika MahlknechtInstitute of General Practice and Public Health, College of Health Care-Professions Claudiana, Bolzano-Bozen, Italy.
Adolf EnglInstitute of General Practice and Public Health, College of Health Care-Professions Claudiana, Bolzano-Bozen, Italy.
Giuliano PiccolioriInstitute of General Practice and Public Health, College of Health Care-Professions Claudiana, Bolzano-Bozen, Italy.
Gernot PfitscherHospital of Bressanone-Brixen (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU), Bressanone-Brixen, Italy.
Philipp SilbernaglHospital of Bressanone-Brixen (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU), Bressanone-Brixen, Italy.
Francesca GiacomoniHospital of Bressanone-Brixen (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU), Bressanone-Brixen, Italy.
Roger PychaHospital of Bressanone-Brixen (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU), Bressanone-Brixen, Italy.
Stefano LombardoStatistical Institute of the Province of Bolzano (ASTAT), Bolzano-Bozen, Italy.
Timon GärtnerStatistical Institute of the Province of Bolzano (ASTAT), Bolzano-Bozen, Italy.
Michael MianInnovation, Research and Teaching Service (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU), Bolzano-Bozen, Italy.
Horand MeierClinical Governance Unit, Administration of the Autonomous Province of Bolzano-Bozen, Bolzano-Bozen, Italy.
Christian J WiedermannInstitute of General Practice and Public Health, College of Health Care-Professions Claudiana, Bolzano-Bozen, Italy.
Roland KeimHospital of Bressanone-Brixen (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU), Bressanone-Brixen, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to (1) describe the course of the emotional burden (i.e., depression, anxiety, and stress) in a general population sample during the coronavirus pandemic in 2020 and 2021 and (2) explore the association between emotional burden and a serologically proven infection with SARS-CoV-2. Study design: This longitudinal study involved a sample of community-dwelling persons aged ≥14 years from the general population of South Tyrol (Province of Bolzano-Bozen, Northern Italy). Data were collected at two stages over a 1-year period in 2020 and 2021. Methods: Persons were invited to participate in a survey on socio-demographic, health-related and psychosocial variables (e.g., age, chronic diseases, Depression Anxiety Stress Scale, DASS-21), as well as in the serological testing for of SARS-CoV-2-specific immunoglobulins. Results: In 2020, 855 (23.8%) out of 3,600 persons participated; in 2021, 305 (35.7%) out of 855 were tested again. We observed a statistically significant decrease in mean DASS-21 scores for depression, stress, and total scores between 2020 and 2021, yet not for anxiety. Persons with a confirmed SARS-CoV-2-infection between the first and second data collection exhibited increased emotional burden compared to those without SARS-CoV-2-infection. The odds of participants with a self-reported diagnosis of mental disorder for future infection with SARS-CoV-2 was almost four times higher than that of participants without mental disorders (OR:3.75; 95%CI:1.79-7.83). Conclusion: Our findings support to the hypothesis of a psycho-neuroendocrine-immune interplay in COVID-19. Further research is necessary to explore the mechanisms underlying the interplay between mental health and SARS-CoV-2 infections.

Indexed as

anxietyCOVID-19depressionemotional burdenlongitudinal studySARS-CoV-2stress

Identifiers

PMID37213392
PMCPMC10197902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.