Evidence map›Paper›PMID 37213075›Full record

ArticleThe Journal of cell biology2023

Macrophage Nrf 2 the rescue.

Jennifer L Stow, Matthew J Sweet

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer L StowInstitute for Molecular Bioscience (IMB), IMB Centre for Cell Biology of Chronic Disease and Australian Infectious Diseases Research Centre, The University of Queensland , Brisbane, Queensland, Australia.ORCID 0000-0002-5409-9101
Matthew J SweetInstitute for Molecular Bioscience (IMB), IMB Centre for Cell Biology of Chronic Disease and Australian Infectious Diseases Research Centre, The University of Queensland , Brisbane, Queensland, Australia.ORCID 0000-0002-0406-8139
The University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exuberant phagocytosis of apoptotic cell corpses by macrophages in Drosophila embryos creates highly oxidative environments. Stow and Sweet discuss work from Clemente and Weavers (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202203062) showing for the first time how macrophage Nrf2 is primed to help sustain immune function and mitigate bystander oxidative damage.

Indexed as

Drosophila ProteinsMacrophagesNF-E2-Related Factor 2PhagocytosisAnimalsApoptosisDrosophilaKelch-Like ECH-Associated Protein 1Oxidative StressDrosophila ProteinsKeap1 protein, DrosophilaKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2

Identifiers

PMID37213075
PMCPMC10203544
OpenAlexW4377220284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.