Evidence map›Paper›PMID 37212673›Full record

ArticleMicrobiology spectrum2023

Variable Region Sequences Influence 16S rRNA Performance.

Nikhil Bose, Sean D Moore

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nikhil BoseBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Sean D MooreBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.ORCID 0000-0003-1606-7771
University of Central Florida · US

Funding

Mechanical Perturbation of Bacterial Translation FidelityR01GM118896 · NIGMS · UNIVERSITY OF CENTRAL FLORIDA · PI MOORE, SEAN DAVID · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM118896
6 · The paper itself

Abstract

16S rRNA gene sequences are commonly analyzed for taxonomic and phylogenetic studies because they contain variable regions that can help distinguish different genera. However, intra-genus distinction using variable region homology is often impossible due to the high overall sequence identities among closely related species, even though some residues may be conserved within respective species. Using a computational method that included the allelic diversity within individual genomes, we discovered that certain Escherichia and

Indexed as

BacteriaShigellaNucleotidesPhylogenyRNA, Ribosomal, 16SNucleotidesRNA, Ribosomal, 16S16S rRNArelative entropyribosome qualitysingle nucleotide polymorphismtaxonomyvariable region

Identifiers

PMID37212673
PMCPMC10269663
OpenAlexW4377220400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.