Evidence map›Paper›PMID 37211821›Full record

ArticleThe neuroradiology journal2023

The proximal balloon occlusion together with direct thrombus aspiration (protect plus) technique: Experience at a tertiary comprehensive stroke center.

Carmen Parra-Fariñas, Jose Danilo Bengzon Diestro, Adam A Dmytriw, Noora Almusalam, Phavalan Rajendram, Rebecca Phillips, Abdullah Alqabbani, Emmad Qazi, Nicholas Hui, Yangmei Li and 5 more

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Article in The neuroradiology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Carmen Parra-FariñasDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-6444-2188
Jose Danilo Bengzon DiestroDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-8450-2021
Adam A DmytriwDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-0131-5699
Noora AlmusalamDivision of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Canada.
Phavalan RajendramDivision of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Canada.
Rebecca PhillipsCumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Abdullah AlqabbaniDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Emmad QaziDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Nicholas HuiFaculty of Medicine, University of New South Wales, Sydney, AU-NSW, Australia.
Yangmei LiDivision of Neurosurgery, Department of Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-7977-1753
Walter MontaneraDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Dipanka SarmaDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Julian SpearsDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Thomas R MarottaDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Aditya BharathaDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTimely restoration of cerebral blood flow using reperfusion therapy is the most effective maneuver for salvaging penumbra. We re-evaluated the previously described PROTECT (PRoximal balloon Occlusion TogEther with direCt Thrombus aspiration during stent retriever thrombectomy) Plus technique at a tertiary comprehensive stroke center.

methodsWe retrospectively analyzed all patients who underwent mechanical thrombectomy with stentrievers between May 2011 and April 2020. Patients were divided between those who underwent PROTECT Plus and those who did not (proximal balloon occlusion with stent retriever only). We compared the groups in terms of reperfusion, groin to reperfusion time, symptomatic intracranial hemorrhage (sICH), modified Rankin Scale (mRS) score at discharge.

resultsWithin the study period, 167 (71.4%) PROTECT Plus and 67 (28.6%) non-PROTECT patients which met our inclusion criteria. There was no statistically significant difference in the number of patients with successful reperfusion (mTICI >2b) between the techniques (85.0% vs 82.1%;

conclusionThe PROTECT Plus technique using a BGC, a distal reperfusion catheter and stent retriever is feasible for recanalization of large vessel occlusions. Successful recanalization, first-pass recanalization and complication rates are similar between PROTECT Plus and non-PROTECT stent retriever techniques. This study adds to an existing body of literature detailing techniques that use both a stent retriever and a distal reperfusion catheter to maximize recanalization for patients with large vessel occlusions.

Indexed as

Balloon OcclusionBrain IschemiaStrokeThrombosisHumansIntracranial HemorrhagesRetrospective StudiesStentsThrombectomyTreatment Outcomeaspirationinterventional neuroradiologystent retrieverStrokethrombectomy

Identifiers

PMID37211821
PMCPMC10649534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.