Evidence map›Paper›PMID 37211657›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Angiographic analysis of ophthalmic artery flow direction in children undergoing chemosurgery for retinoblastoma compared to age-matched controls.

Michael Feldman, Heather Grimaudo, Steven Roth, Nishit Mummareddy, Haley Vance, Anthony B Daniels, Michael T Froehler

Open access · hybridAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Michael FeldmanDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-8979-3128
Heather GrimaudoDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Steven RothDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Nishit MummareddyDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Haley VanceDivision of Pediatric Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Anthony B DanielsDepartment of Ophthalmology, Vanderbilt Eye Center, Nashville, Tennessee, USA.
Michael T FroehlerCerebrovascular Program, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0003-1282-005X
Neurological Surgery · USVanderbilt University Medical Center · USVanderbilt Health · US

Funding

Developing alternative approaches to reduce retinal toxicity and prevent vision loss in the treatment of intraocular retinoblastomaK08EY027464 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DANIELS, ANTHONY BRENT · 2017 to 2021
$960k
NEI NIH HHS K08 EY027464
6 · The paper itself

Abstract

PurposeCatheter-based intra-arterial chemotherapy (IAC) has revolutionized the treatment of retinoblastoma (RB). Variability in ophthalmic artery (OA) flow, either retrograde from external carotid artery branches, or anterograde from the internal carotid artery, necessitates multiple IAC techniques. We evaluated the direction of OA flow and identify OA flow reversal events over the course of IAC treatment as well in comparison to OA flow direction in non-RB children.Materials and MethodsWe performed a retrospective analysis of OA flow direction in all RB patients treated with IAC, along with an age-matched control group who underwent cerebral angiography at our center from 2014 to 2020.ResultsIAC was administered to a total of 18 eyes (15 patients). Initial anterograde OA flow was demonstrated in 66% (

Indexed as

Cerebral AngiographyOphthalmic ArteryRetinal NeoplasmsRetinoblastomaAntineoplastic AgentsCase-Control StudiesChildChild, PreschoolFemaleHumansInfantInfusions, Intra-ArterialMaleMelphalanRetrospective StudiesAntineoplastic AgentsMelphalanIntra-arterial chemotherapyophthalmic arteryretinoblastomavascular anatomy

Identifiers

PMID37211657
PMCPMC12475354
OpenAlexW4377220480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.