Evidence map›Paper›PMID 37210887›Full record

Trial reportBehaviour research and therapy2023

Optimizing outcomes, mechanisms, and recall of Cognitive Therapy for depression: Dose of constructive memory support strategies.

Laurel D Sarfan, Garret Zieve, Nicole B Gumport, Mo Xiong, Allison G Harvey

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behaviour research and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laurel D SarfanUniversity of California, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: sarfanld@berkeley.edu.
Garret ZieveUniversity of California, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: ggzieve@berkeley.edu.
Nicole B GumportUniversity of California, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: ngumport@stanford.edu.
Mo XiongUniversity of California, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: mxiong1@berkeley.edu.
Allison G HarveyUniversity of California, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: aharvey@berkeley.edu.

Funding

Improving Depression Outcome by Enhancing Memory for Cognitive TherapyR01MH108657 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARVEY, ALLISON G · 2016 to 2019
$3.0M
Advancing Sustainability of Evidence-Based Treatments in Community Mental HealthF32MH131284 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI SARFAN, LAUREL D · 2022 to 2024
$76k
NIMH NIH HHS F32 MH131284NIMH NIH HHS R01 MH108657
6 · The paper itself

Abstract

objectivePoor memory for treatment is associated with worse patient outcomes. Therapist use of constructive memory support strategies, which help patients actively engage with treatment content, may improve patient memory for treatment. We sought to identify the dose of constructive memory support needed to optimize treatment outcomes, mechanisms, and patient recall.

methodAdults with major depressive disorder (N = 178, mean age = 37.9, 63% female, 17% Hispanic or Latino/a) were randomized to Cognitive Therapy plus a Memory Support Intervention or Cognitive Therapy as usual. Because therapists from both groups used constructive memory support, treatment conditions were combined to maximize data. Depression and overall impairment were assessed before treatment, immediately post-treatment (POST), and six (6FU) and 12 months (12FU) after treatment. Patients completed measures of treatment mechanisms - utilization/competency in Cognitive Therapy skills - and treatment recall at POST, 6FU, and 12FU. Patient adherence to treatment was averaged across sessions.

resultsUsing Kaplan-Meier Survival Analyses, the optimal dose of constructive memory support was eight uses per session (sensitivity analysis range: 5-12 uses). Pre-treatment depression symptoms and patient perceptions of treatment may impact the optimal dose.

conclusionEight uses of constructive memory support by therapists per session may optimize treatment outcomes, mechanisms, and recall over the long-term.

Indexed as

Cognitive Behavioral TherapyMajor Depressive DisorderAdultDepressionFemaleHumansMaleMemoryMental RecallTreatment OutcomeCognitive therapyDose-responseMajor depressive disorderMemory supportTransdiagnostic

Identifiers

PMID37210887
PMCPMC10513748

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.