Evidence map›Paper›PMID 37210789›Full record

ReviewCurrent opinion in plant biology2023

Non-canonical and developmental roles of the TCA cycle in plants.

Tao Zhang, Jesus T Peng, Amman Klair, Alexandra J Dickinson

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in plant biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Transcriptomic and metabolomic profiling ofFrontiers in plant science · 2026
    Article
  8. Article
  9. Intrinsic and induced metabolic signatures underpin aluminum tolerance in bread wheat: a comparative metabolomics approach.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tao ZhangCell and Developmental Biology, University of California San Diego, La Jolla, CA, USA.
Jesus T PengCell and Developmental Biology, University of California San Diego, La Jolla, CA, USA.
Amman KlairCell and Developmental Biology, University of California San Diego, La Jolla, CA, USA.
Alexandra J DickinsonCell and Developmental Biology, University of California San Diego, La Jolla, CA, USA. Electronic address: adickinson@ucsd.edu.
University of California San Diego · US

Funding

Illuminating the chemical biology of stem cell decisions in plant rootsR35GM147216 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Alexandra Jazz Dickinson · 2022 to 2026
$2.0M
NIGMS NIH HHS R35 GM147216
6 · The paper itself

Abstract

Over recent years, our understanding of the tricarboxylic acid cycle (TCAC) in living organisms has expanded beyond its canonical role in cellular energy production. In plants, TCAC metabolites and related enzymes have important roles in physiology, including vacuolar function, chelation of metals and nutrients, photorespiration, and redox regulation. Research in other organisms, including animals, has demonstrated unexpected functions of the TCAC metabolites in a number of biological processes, including signaling, epigenetic regulation, and cell differentiation. Here, we review the recent progress in discovery of non-canonical roles of the TCAC. We then discuss research on these metabolites in the context of plant development, with a focus on research related to tissue-specific functions of the TCAC. Additionally, we review research describing connections between TCAC metabolites and phytohormone signaling pathways. Overall, we discuss the opportunities and challenges in discovering new functions of TCAC metabolites in plants.

Indexed as

Citric Acid CycleEpigenesis, GeneticAnimalsPlant DevelopmentPlant Growth RegulatorsPlantsPlant Growth RegulatorsPhytohormonesPlant developmentPrimary metabolismTricarboxylic acid cycle

Identifiers

PMID37210789
PMCPMC10524895
OpenAlexW4377090493

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.