Evidence map›Paper›PMID 37210736›Full record

ArticleSchizophrenia bulletin2023

Age-Related Social Cognitive Performance in Individuals With Psychotic Disorders and Their First-Degree Relatives.

Eva Velthorst, Adam Socrates, GROUP Investigators, Behrooz Z Alizadeh, Therese van Amelsvoort, Agna A Bartels-Velthuis, Richard Bruggeman, Wiepke Cahn, Lieuwe de Haan, Frederike Schirmbeck and 3 more

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Eva VelthorstDepartment of Research, Mental Health Organization "GGZ Noord-Holland-Noord," Heerhugowaard, The Netherlands.ORCID 0000-0002-9240-2909
Adam SocratesDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
GROUP Investigators
Behrooz Z AlizadehRob Giel Research Center, University of Groningen, University Medical Center Groningen, University Center for Psychiatry, Groningen, The Netherlands.
Therese van AmelsvoortDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Agna A Bartels-VelthuisRob Giel Research Center, University of Groningen, University Medical Center Groningen, University Center for Psychiatry, Groningen, The Netherlands.
Richard BruggemanRob Giel Research Center, University of Groningen, University Medical Center Groningen, University Center for Psychiatry, Groningen, The Netherlands.
Wiepke CahnUniversity Medical Center Utrecht, Department of Psychiatry, Brain Centre Rudolf Magnus, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-0482-8759
Lieuwe de HaanSeaver Center for Autism Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Frederike SchirmbeckSeaver Center for Autism Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Claudia J P SimonsDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0002-7637-3589
Jim van OsUniversity Medical Center Utrecht, Department of Psychiatry, Brain Centre Rudolf Magnus, Utrecht University, Utrecht, The Netherlands.
Anne-Kathrin FettDepartment of Psychology, City, University of London, London, UK.

Funding

Dutch Health Research Council 10-000-1001
6 · The paper itself

Abstract

backgroundSocial cognitive impairment is a recognized feature of psychotic disorders. However, potential age-related differences in social cognitive impairment have rarely been studied. STUDY

designData came from 905 individuals with a psychotic disorder, 966 unaffected siblings, and 544 never-psychotic controls aged 18-55 who participated in the Genetic Risk and Outcome of Psychosis (GROUP) study. Multilevel linear models were fitted to study group main effects and the interaction between group and age on emotion perception and processing (EPP; degraded facial affect recognition) and theory of mind (ToM; hinting task) performance. Age-related differences in the association between socio-demographic and clinical factors, and EPP and ToM were also explored. STUDY

resultsAcross groups, EPP performance was associated with age (β = -0.02, z = -7.60, 95% CI: -0.02, -0.01, P < .001), with older participants performing worse than younger ones. A significant group-by-age interaction on ToM (X2(2) = 13.15, P = .001) indicated that older patients performed better than younger ones, while no age-related difference in performance was apparent among siblings and controls. In patients, the association between negative symptoms and ToM was stronger for younger than older patients (z = 2.16, P = .03).

conclusionsThe findings point to different age-related performance patterns on tests of 2 key social cognitive domains. ToM performance was better in older individuals, although this effect was only observed for patients. EPP was less accurate in older compared with younger individuals. These findings have implications with respect to when social cognitive training should be offered to patients.

Indexed as

Cognitive DysfunctionPsychotic DisordersSchizophreniaTheory of MindAgedCognitionEmotionsHumansNeuropsychological Testsagingfunctional impairmentpsychosisschizophreniasiblingssocial cognition

Identifiers

PMID37210736
PMCPMC10686369

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.