Evidence map›Paper›PMID 37210580›Full record

ArticleEuropean heart journal. Acute cardiovascular care2023

Poorer survival after out-of-hospital cardiac arrest among cancer patients: a population-based register study.

Hanna L Hägglund, Martin Jonsson, Elham Hedayati, Christel Hedman, Therese Djärv

Open access · hybridAbstract read
In one paragraph

Article in European heart journal. Acute cardiovascular care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hanna L HägglundDepartment of Medicine, Karolinska Institutet, Karolinska University Hospital, D1: 04. 171 76 Stockholm, Sweden.ORCID 0000-0002-7144-2741
Martin JonssonDepartment of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden.ORCID 0000-0002-3539-8317
Elham HedayatiDepartment of Oncology-Pathology, Karolinska Institutet, Solna, Sweden.ORCID 0000-0003-1352-4332
Christel HedmanDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
Therese DjärvDepartment of Medicine, Karolinska Institutet, Karolinska University Hospital, D1: 04. 171 76 Stockholm, Sweden.
Karolinska University Hospital · SELund University · SEStockholm South General Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe association between cancer and survival after out-of-hospital cardiac arrest (OHCA) has not been thoroughly investigated. We aimed to address this knowledge gap using national, population-based registries. METHODS AND

resultsFor this study, 30 163 patients with OHCA (≥18 years) were included from the Swedish Register of Cardiopulmonary Resuscitation. Through linkage to the National Patient Registry, 2894 patients (10%) with cancer diagnosed within 5 years prior to OHCA were identified. Differences in 30-day survival between patients with cancer and controls (defined as patients with OHCA without previous cancer diagnosis) were assessed related to cancer stage (locoregional vs. metastasized cancer) and cancer site (e.g. lung cancer, breast cancer, etc.) using logistic regression adjusted for prognostic factors. Long-term survival was presented as a Kaplan-Meier curve. For locoregional cancer, no statistically significant difference in return of spontaneous circulation (ROSC) was seen compared with controls, and metastasized disease was associated with a poorer chance of ROSC. Cancer was associated with a lower 30-day survival for all cancers [adjusted odds ratio (OR) 0.57, confidence interval (CI) 0.49-0.66], locoregional cancer (adjusted OR 0.68, CI 0.57-0.82), and metastasized cancer (adjusted OR 0.24, CI 0.14-0.40) compared with controls. A lower 30-day survival compared with controls was seen for lung, gynaecological and haematological cancers.

conclusionCancer is associated with poorer 30-day survival after OHCA. This study suggests that cancer site and disease stage are more relevant factors than cancer in general with regard to its effect on survival after OHCA.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesNeoplasmsOut-of-Hospital Cardiac ArrestHumansLogistic ModelsRegistriesCardiac arrestCardio-oncologyComorbidityMalignancySurvival

Identifiers

PMID37210580
PMCPMC10449376
OpenAlexW4377134091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.