ArticleCardiovascular ultrasound2023
Noninvasive right ventricular work in patients with atrial septal defects: a proof-of-concept study.
Article in Cardiovascular ultrasound, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Right Ventricular Myocardial Work by Echocardiography: A Scoping Review of Methodology, Validation, and Clinical Applications.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Accuracy and reliability of non-invasive pressure-strain loop for myocardial work assessment in functional single ventricle patients.BMC cardiovascular disorders · 2025Article
- Right Heart Evaluation: A Tough Challenge for Clinicians.Life (Basel, Switzerland) · 2025Review
- Assessing subaortic right ventricle function after atrial switch repair through myocardial work analysis.International journal of cardiology. Congenital heart disease · 2024Article
- The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation.Frontiers in cardiovascular medicine · 2024Review
- Echocardiography Imaging of the Right Ventricle: Focus on Three-Dimensional Echocardiography.Diagnostics (Basel, Switzerland) · 2023Review
- Clinical Applications of Myocardial Work in Echocardiography: A Comprehensive Review.Journal of cardiovascular echographyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNoninvasive right ventricular (RV) myocardial work (RVMW) determined by echocardiography is a novel indicator used to estimate RV systolic function. To date, the feasibility of using RVMW has not been verified in assessing RV function in patients with atrial septal defect (ASD).
methodsNoninvasive RVMW was analysed in 29 ASD patients (median age, 49 years; 21% male) and 29 age- and sex-matched individuals without cardiovascular disease. The ASD patients underwent echocardiography and right heart catheterization (RHC) within 24 h.
resultsThe RV global work index (RVGWI), RV global constructive work (RVGCW), and RV global wasted work (RVGWW) were significantly higher in the ASD patients than in the controls, while there was no significant difference in RV global work efficiency (RVGWE). RV global longitudinal strain (RV GLS), RVGWI, RVGCW, and RVGWW demonstrated significant correlations with RHC-derived stroke volume (SV) and SV index. The RVGWI (area under receiver operating characteristic curve [AUC] = 0.895), RVGCW (AUC = 0.922), and RVGWW (AUC = 0.870) could be considered good predictors of ASD and were superior to RV GLS (AUC = 0.656).
conclusionThe RVGWI, RVGCW, and RVGWW could be used to assess RV systolic function and are correlated with RHC-derived SV and SV index in patients with ASD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.