Evidence map›Paper›PMID 37210494›Full record

ArticleBMC gastroenterology2023

Peripheral CD4

Junlan Qiu, Weiqiang Shi, Jin Zhang, Qinqin Gao, Lin Feng, Zhixiang Zhuang

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Programmed Cell Death Protein 1-Interleukin-2 Bispecific Agents for Cancer Therapy.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Junlan Qiu *Department of Oncology, Suzhou Science and Technology Town Hospital, Suzhou, Jiangsu, 215153, China. qiujunland@163.com.
Weiqiang Shi *Department of Pathology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China.
Jin ZhangDepartment of Pathology, Suzhou Science and Technology Town Hospital, Suzhou, Jiangsu, 215153, China.
Qinqin GaoInstitute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China.
Lin FengDepartment of Oncology, Suzhou Science and Technology Town Hospital, Suzhou, Jiangsu, 215153, China.
Zhixiang ZhuangDepartment of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
Suzhou University of Science and Technology · CNFirst Affiliated Hospital of Soochow University · CNSecond Affiliated Hospital of Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegulatory T cells (Tregs) play an important role in regulation of immune response and immunologic tolerance in cancer. Gastrointestinal cancer is still a leading cause of cancer-related death in the world. This study aimed to detect Tregs in patients with gastrointestinal cancer.

methodsIn this study, 45 gastric cancer patients, 50 colorectal cancer patients and 50 healthy controls were enrolled. Flow cytometry was used to detect CD4

resultsCompared with healthy controls, the levels of CD4

conclusionThe present study firstly demonstrated that gastrointestinal patients have a compromised immune status where the CD4

Indexed as

Stomach NeoplasmsT-Lymphocytes, RegulatoryCD4-Positive T-LymphocytesFlow CytometryForkhead Transcription FactorsHumansInterleukin-10Interleukin-2 Receptor alpha SubunitTransforming Growth Factor beta1Forkhead Transcription FactorsInterleukin-10Interleukin-2 Receptor alpha SubunitTransforming Growth Factor beta1CD4+CD25hiCD127low TregsGastrointestinal cancerIL-10TGF-β1

Identifiers

PMID37210494
PMCPMC10199496
OpenAlexW4377157569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.