Evidence map›Paper›PMID 37210385›Full record

ArticleNPJ science of food2023

Ginger essential oil and citral ameliorates atherosclerosis in ApoE

Suraphan Panyod, Wei-Kai Wu, Sin-Yi Peng, Yea-Jing Tseng, Ya-Chi Hsieh, Rou-An Chen, Huai-Syuan Huang, Yi-Hsun Chen, Hsiao-Li Chuang, Cheng-Chih Hsu and 5 more

Open access · goldAbstract read
In one paragraph

Article in NPJ science of food, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Protective role of aqueousFrontiers in endocrinology · 2026
    Article
  8. Review
  9. The Role of the Gut Microbiota in Vascular Physiology and Health.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Advances in essential oils for metabolic diseases.Frontiers in endocrinology · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Effects of Ginger (Biomolecules · 2024
    Review
  19. The footprint of gut microbiota in gallbladder cancer: a mechanistic review.Frontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Suraphan Panyod *Institute of Food Science and Technology, National Taiwan University, Taipei, Taiwan, ROC.ORCID http://orcid.org/0000-0001-8998-375X
Wei-Kai Wu *Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan, ROC.ORCID http://orcid.org/0000-0002-9476-8998
Sin-Yi PengInstitute of Food Science and Technology, National Taiwan University, Taipei, Taiwan, ROC.
Yea-Jing TsengInstitute of Food Science and Technology, National Taiwan University, Taipei, Taiwan, ROC.
Ya-Chi HsiehInstitute of Food Science and Technology, National Taiwan University, Taipei, Taiwan, ROC.
Rou-An ChenInstitute of Food Science and Technology, National Taiwan University, Taipei, Taiwan, ROC.
Huai-Syuan HuangInstitute of Food Science and Technology, National Taiwan University, Taipei, Taiwan, ROC.
Yi-Hsun ChenDepartment of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.
Hsiao-Li ChuangNational Laboratory Animal Center, National Applied Research Laboratories, Taipei, Taiwan, ROC.
Cheng-Chih HsuDepartment of Chemistry, National Taiwan University, Taipei, Taiwan, ROC.ORCID http://orcid.org/0000-0002-2892-5326
Ting-Chin David ShenDivision of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, USA.
Kai-Chien YangDepartment and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.
Chi-Tang HoDepartment of Food Science, Rutgers University, New Brunswick, NJ, USA.
Ming-Shiang WuDepartment of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC. mingshiang@ntu.edu.tw.ORCID http://orcid.org/0000-0002-1940-6428
Lee-Yan SheenInstitute of Food Science and Technology, National Taiwan University, Taipei, Taiwan, ROC. lysheen@ntu.edu.tw.ORCID http://orcid.org/0000-0001-5541-652X
National Taiwan University · TWNational Institutes of Applied Research · TWNational Taiwan University of Science and Technology · TWRutgers, The State University of New Jersey · USUniversity of Pennsylvania · US

Funding

Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) 109-2314-B-002-064-MY3Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) 109-2327-B-002-005
6 · The paper itself

Abstract

Recently, the role of the gut microbiota in diseases, including cardiovascular disease (CVD), has gained considerable research attention. Trimethylamine-N-oxide (TMAO), which is formed during ʟ-carnitine metabolism, promotes the formation of atherosclerotic plaques, causing thrombosis. Here, we elucidated the anti-atherosclerotic effect and mechanism of ginger (Zingiber officinale Roscoe) essential oil (GEO) and its bioactive compound citral in Gubra Amylin NASH (GAN) diet with ʟ-carnitine-induced atherosclerosis female ApoE

Identifiers

PMID37210385
PMCPMC10199921
OpenAlexW4377157188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.