Evidence map›Paper›PMID 37210158›Full record

ArticleAmerican journal of preventive medicine2023

Trends in Emergency Department Visits for Unsupervised Pediatric Medication Exposures.

Maribeth C Lovegrove, Nina J Weidle, Andrew I Geller, Jennifer N Lind, Kathleen O Rose, Sandra K Goring, Daniel S Budnitz

Open access · bronzeAbstract read
In one paragraph

Article in American journal of preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maribeth C LovegroveDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: MLovegrove@cdc.gov.
Nina J WeidleDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia; Eagle Global Scientific, LLC, Atlanta, Georgia.
Andrew I GellerDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jennifer N LindDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Kathleen O RoseDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia; Chenega Enterprise Systems and Solutions, Atlanta, Georgia.
Sandra K GoringDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia; Chenega Enterprise Systems and Solutions, Atlanta, Georgia.
Daniel S BudnitzDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Centers for Disease Control and Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

introductionEmergency department visits and hospitalizations for unsupervised medication exposures among young children increased in the early 2000s. Prevention efforts were initiated in response.

methodsNationally representative data from the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project collected from 2009 to 2020 were analyzed in 2022 to assess overall and medication-specific trends in emergency department visits for unsupervised exposures among children aged ≤5 years.

resultsFrom 2009 to 2020, there were an estimated 677,968 (95% CI=550,089, 805,846) emergency department visits for unsupervised medication exposures among children aged ≤5 years in the U.S. Most visits involved children aged 1-2 years (2009-2012 [70.3%], 2017-2020 [67.4%]), and nearly one half involved prescription solid medications (2009-2012 [49.4%], 2017-2020 [48.1%]). The largest declines in estimated numbers of annual visits from 2009-2012 to 2017-2020 were for exposures involving prescription solid benzodiazepines (-2,636 visits, -72.0%) and opioids (-2,596 visits, -53.6%) and over-the-counter liquid cough and cold medications (-1,954 visits, -71.6%) and acetaminophen (-1,418 visits, -53.4%). The estimated number of annual visits increased for exposures involving over-the-counter solid herbal/alternative remedies (+1,028 visits, +65.6%), with the largest increase for melatonin exposures (+1,440 visits, +421.1%). Overall, the estimated number of visits for unsupervised medication exposures decreased from 66,416 in 2009 to 36,564 in 2020 (annual percentage change= -6.0%). Emergent hospitalizations for unsupervised exposures also declined (annual percentage change= -4.5%).

conclusionsDeclines in estimated emergency department visits and hospitalizations for unsupervised medication exposures from 2009 to 2020 coincided with renewed prevention efforts. Targeted approaches may be needed to achieve continued declines in unsupervised medication exposures among young children.

Indexed as

Drug-Related Side Effects and Adverse ReactionsPrescription DrugsBenzodiazepinesChildChild, PreschoolEmergency Service, HospitalHospitalizationHumansNonprescription DrugsUnited StatesBenzodiazepinesNonprescription DrugsPrescription Drugs

Identifiers

PMID37210158
PMCPMC10935594
OpenAlexW4366529667

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.