Evidence map›Paper›PMID 37210081›Full record

ArticleEuropean heart journal2023

A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers.

Remco de Brouwer, Wouter P Te Rijdt, Edgar T Hoorntje, Ahmad Amin, Folkert W Asselbergs, Moniek G P J Cox, Jeroen F van der Heijden, Hans Hillege, Jacco C Karper, Belend Mahmoud and 14 more

Abstract read
In one paragraph

Article in European heart journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. 2023 European Society of Cardiology guidelines on the management of cardiomyopathies : Statement of endorsement by the NVVC.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025
    Article
  6. Should we offer preventive treatment to all carriers of PLN p.(Arg14del) variant? : Pro: Provide pre-emptive treatment to asymptomatic carriers.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2023
    Review
  7. Should we offer preventive treatment to all carriers of PLN p.(Arg14del) variant? : Con: Do no harm to asymptomatic carriers.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Remco de BrouwerDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.ORCID 0000-0002-5705-2034
Wouter P Te RijdtDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.ORCID 0000-0003-4852-9379
Edgar T HoorntjeNetherlands Heart Institute, Utrecht, the Netherlands.ORCID 0000-0002-8326-7717
Ahmad AminDepartment of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.
Folkert W AsselbergsDepartment of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-1692-8669
Moniek G P J CoxDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Jeroen F van der HeijdenDepartment of Cardiology, Division Heart & Lungs, Utrecht University Medical Centre, Utrecht, the Netherlands.
Hans HillegeDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.ORCID 0000-0001-7397-1148
Jacco C KarperDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Belend MahmoudDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Peter van der MeerDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Anton OomenDepartment of Cardiology, Antonius Hospital, Sneek, the Netherlands.
Anneline S J M Te RieleDepartment of Cardiology, Division Heart & Lungs, Utrecht University Medical Centre, Utrecht, the Netherlands.
Herman H W SilljéDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Hanno L TanNetherlands Heart Institute, Utrecht, the Netherlands.ORCID 0000-0002-7905-5818
Jan Peter van TintelenNetherlands Heart Institute, Utrecht, the Netherlands.
Dirk J van VeldhuisenDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.ORCID 0000-0003-1611-7935
Berend Daan WestenbrinkDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Ans C P WiesfeldDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Tineke P WillemsDepartment of Radiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Paul A van der ZwaagDepartment of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Arthur A M WildeDepartment of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-0528-0852
Rudolf A de BoerDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.ORCID 0000-0002-4775-9140
Maarten P van den BergDepartment of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.ORCID 0000-0002-1493-2998

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CardiomyopathyEplerenoneFibrosisHeart failurePhospholambanRandomized clinical trial

Identifiers

PMID37210081
PMCPMC10590125

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.