ReviewNeuroscience and biobehavioral reviews2023
The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery.
Review in Neuroscience and biobehavioral reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07692412 (Multisensory Therapy Alleviating MRI-Related Anxiety in Cancer Patients Via Brain-Autonomic Network Modulation), which is not on this map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multisensory Therapy Alleviating MRI-Related Anxiety in Cancer Patients Via Brain-Autonomic Network Modulation: A Randomized Clinical Trial
Who cites it
35 citing papers in PubMed.
- Trial
- Anxiety disorders: a cross-sectional study of clinical and biological associations.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Olfactory tubercle mediates adaptive social behavior by controlling threat assessment and the expression of social threat memories during recall in male mice.Nature communications · 2026Article
- Anxiety disorders alter cognitive-motor integration during visuomotor adaptation and retention.Experimental brain research · 2026Article
- Cyber-victimized and cognitively fogged? Cyberbullying victimization and executive function.BMC public health · 2026Article
- Neuroproteomic Profiling of the Anxiolytic Potential ofInternational journal of molecular sciences · 2026Article
- Worth the Wait? The Effect of Comparative Framing on Tourists' Waiting Intention.Behavioral sciences (Basel, Switzerland) · 2026Article
- Fear, anxiety, and the extended amygdala-absence of evidence for strict functional segregation.Social cognitive and affective neuroscience · 2026Article
- Anxiety is associated with systemic pro-inflammatory profile and plasma lipid changes in Mexican young adults.Frontiers in cellular neuroscience · 2026Article
- Cracking the Valence Code: Patterned Facial Kinematics and Neural Signatures of Emotional Expressions in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Fear, anxiety, and the extended amygdala-bioRxiv : the preprint server for biology · 2025Article
- Brain Tumors, AI and Psychiatry: Predicting Tumor-Associated Psychiatric Syndromes with Machine Learning and Biomarkers.International journal of molecular sciences · 2025Review
- Social anxiety and gratitude among children left behind due to migration in western rural China.Scientific reports · 2025Article
- Fear Circuits in Panic Disorder: An Update.Alpha psychiatry · 2025Review
- A Shared Threat-Anticipation Circuit Is Dynamically Engaged at Different Moments by Certain and Uncertain Threat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The impact of experiential avoidance on anxiety and depressive disorders in hematological cancer patients.Journal of behavioral medicine · 2025Observational
- A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat.bioRxiv : the preprint server for biology · 2025Article
- Navigating the fear: assessing nursing students' concerns and preventive practices in response to Monkeypox in Egypt.BMC nursing · 2025Article
- Mental health burden among healthcare workers in Kintampo North Municipal Hospital: A descriptive analysis of stress, depression, and anxiety based on Job Demands-Resources (JD-R) model.PLOS mental health · 2025Article
- Neural circuit basis of pathological anxiety.Nature reviews. Neuroscience · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
Fear and anxiety play a central role in mammalian life, and there is considerable interest in clarifying their nature, identifying their biological underpinnings, and determining their consequences for health and disease. Here we provide a roundtable discussion on the nature and biological bases of fear- and anxiety-related states, traits, and disorders. The discussants include scientists familiar with a wide variety of populations and a broad spectrum of techniques. The goal of the roundtable was to take stock of the state of the science and provide a roadmap to the next generation of fear and anxiety research. Much of the discussion centered on the key challenges facing the field, the most fruitful avenues for future research, and emerging opportunities for accelerating discovery, with implications for scientists, funders, and other stakeholders. Understanding fear and anxiety is a matter of practical importance. Anxiety disorders are a leading burden on public health and existing treatments are far from curative, underscoring the urgency of developing a deeper understanding of the factors governing threat-related emotions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.