Evidence map›Paper›PMID 37209667›Full record

ArticleEmerging infectious diseases2023

Neurologic Complications of Babesiosis, United States, 2011-2021.

Sara Locke, Jane O'Bryan, Adeel S Zubair, Melissa Rethana, Anne Spichler Moffarah, Peter J Krause, Shelli F Farhadian

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Pathogens (Basel, Switzerland) · 2025
    Article
  6. Tick-induced neurological disorders.Journal of neurology · 2025
    Review
  7. Review
  8. Journal of central nervous system disease · 2025
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sara Locke
Jane O'Bryan
Adeel S Zubair
Melissa Rethana
Anne Spichler Moffarah
Peter J Krause
Shelli F Farhadian
Quinnipiac University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NIA Short Term Research Training: Students in Health Professional SchoolsT35AG049685 · NIA · YALE UNIVERSITY · PI Sarwat I Chaudhry, Terri R. Fried · 2016 to 2026
$804k
Understanding the cellular basis for persistent immune activation in the central nervous system during virologically suppressed HIVK23MH118999 · NIMH · YALE UNIVERSITY · PI FARHADIAN, SHELLI · 2018 to 2021
$770k
NCATS NIH HHS UL1 TR001863NIA NIH HHS T35 AG049685NIMH NIH HHS K23 MH118999
6 · The paper itself

Abstract

Babesiosis is a globally distributed parasitic infection caused by intraerythrocytic protozoa. The full spectrum of neurologic symptoms, the underlying neuropathophysiology, and neurologic risk factors are poorly understood. Our study sought to describe the type and frequency of neurologic complications of babesiosis in a group of hospitalized patients and assess risk factors that might predispose patients to neurologic complications. We reviewed medical records of adult patients who were admitted to Yale-New Haven Hospital, New Haven, Connecticut, USA, during January 2011-October 2021 with laboratory-confirmed babesiosis. More than half of the 163 patients experienced >1 neurologic symptoms during their hospital admissions. The most frequent symptoms were headache, confusion/delirium, and impaired consciousness. Neurologic symptoms were associated with high-grade parasitemia, renal failure, and history of diabetes mellitus. Clinicians working in endemic areas should recognize the range of symptoms associated with babesiosis, including neurologic.

Indexed as

Babesia microtiBabesiosisNervous System DiseasesAdultConnecticutHumansParasitemiaUnited StatesBabesia microtibabesiosisneurologyparasitesUnited States

Identifiers

PMID37209667
PMCPMC10202888
OpenAlexW4377198097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.