SynthesisArchives of orthopaedic and trauma surgery2023
Incidence and risk factors for complex regional pain syndrome in radius fractures: meta-analysis.
Synthesis in Archives of orthopaedic and trauma surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Incidence and Patient-Level Risk Factors for Complex Regional Pain Syndrome Following Cubital Tunnel Surgery.Journal of hand surgery global online · 2026Article
- Risk Factors and Prevention Strategies for Complex Regional Pain Syndrome Following Fractures: A Scoping Review.Cureus · 2026Review
- Incidence proportion of complex regional pain syndrome (CRPS) after distal radius fracture: a population-based register study.Acta orthopaedica · 2026Article
- Management of Distal Radius Fractures in Frail Elderly Patients With High Anesthetic Risk: Cast Immobilization Versus Volar Locking Plate Fixation.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- The Warm Phase of CRPS Type-1: Is It Time to Review the Budapest Criteria?Diagnostics (Basel, Switzerland) · 2025Article
- Poor fracture alignment equals poor outcome? Analysis of conservatively managed distal radius fractures.Archives of orthopaedic and trauma surgery · 2025Article
- Locking pegs versus locking screws in volar plating of distal radius fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Hidden dangers of pelvic fracture: A meta-analysis on urinary tract injury incidence and risk factors.World journal of orthopedics · 2025Article
- Does the AO/OTA fracture classification dictate the anesthesia modality for the surgical management of unstable distal radius fractures? - A retrospective cohort study in 127 patients managed by general vs. regional anesthesia.Patient safety in surgery · 2025Article
- Comprehensive Mechanisms and Non-Invasive Treatment for Complex Regional Pain Syndrome: A Narrative Review.Journal of pain research · 2025Review
- Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction.BMC musculoskeletal disorders · 2024Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis meta-analysis aimed to evaluate the incidence and risk factors for complex regional pain syndrome (CRPS) in radius fractures.
methodsThe meta-analysis was performed using the PubMed, Embase, Scopus, and Cochrane Collaboration Library databases. Studies focusing on patients with conservative or surgically treated radius fractures leading to CRPS were included. A control group consisting of patients with radius fractures and no CRPS (-) was included. The outcome measures were incidence and risk factors. Comparative studies were also included. Data were combined using Review Manager 5.4.
resultsOut of 610 studies, nine studies were included. The incidence of CRPS after radius fractures ranged from 0.19 to 13.63% (95% CI: 11.12-16.15%). Open fractures, high-energy mechanisms in radial head fractures, and associations with ulnar fractures were risk factors for CRPS [(RR: 0.98; 95% CI: 0.97-1.00), (RR: 0.18; 95% CI: 0.07-0.47), and (RR: 1.25; 95% CI: 1.17-1.35), respectively]. Other risk factors were female sex and high body mass index [(RR: 1.20; 95% CI: 1.05-1.37) and (MD: 1.17; 95% CI: 0.45-1.88)]. Psychiatric factors also increased the incidence of CRPS (RR: 2.04; 95% CI: 1.83-2.28). On the other hand, the type of surgery (external fixation or open reduction and internal fixation) and manipulations; associated comorbidities (diabetes and hypertension) together with tobacco and alcohol abuse; marital status, educational level, employment status, and socioeconomic status were not risk factors (p > 0.05).
conclusionThe incidence of CRPS in radius fractures was 13.63%. Fractures with greater complexity or greater associated tissue damage, female sex, high BMI, and psychiatric disorders were risk factors for the development of CRPS. LEVEL OF EVIDENCE: Meta-analysis of cohort and case series studies; II.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.