Evidence map›Paper›PMID 37209157›Full record

ArticleInternational journal of clinical oncology2023

Longitudinal health-related quality of life analysis in childhood cancer survivors after proton beam therapy.

Hiroko Fukushima, Ryoko Suzuki, Yuni Yamaki, Sho Hosaka, Masako Inaba, Kouji Masumoto, Ai Muroi, Takao Tsurubuchi, Reiko Okubo, Kyoko Hidaka and 3 more

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Article in International journal of clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hiroko FukushimaDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Japan. fkhiroko@md.tsukuba.ac.jp.ORCID http://orcid.org/0000-0002-1290-3501
Ryoko SuzukiDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Japan.
Yuni YamakiDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Japan.
Sho HosakaDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Japan.
Masako InabaDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Japan.
Kouji MasumotoDepartment of Pediatric Surgery, University of Tsukuba Hospital, Tsukuba, Japan.
Ai MuroiDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Takao TsurubuchiDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Reiko OkuboDepartment of Health Care Policy and Health Economics, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Kyoko HidakaDepartment of Clinical Psychology, University of Tsukuba Hospital, Tsukuba, Japan.
Masashi MizumotoDepartment of Radiation Oncology, University of Tsukuba Hospital, Tsukuba, Japan.
Hideyuki SakuraiDepartment of Radiation Oncology, University of Tsukuba Hospital, Tsukuba, Japan.
Hidetoshi TakadaDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Japan.
University of Tsukuba Hospital · JPUniversity of Tsukuba · JP

Funding

Foundation for Promotion of Cancer Research A-26Pfizer Health Research Foundation 18Y10
6 · The paper itself

Abstract

purposeWhilst proton beam therapy (PBT) for children with cancer is expected to reduce their comorbidities, to date only a limited number of studies have been published. To analyze the long-term comorbidity and health-related quality of life (HRQoL) of childhood cancer survivors (CCSs) after PBT, we conducted a questionnaire-based study.

methodsQuestionnaires were sent to CCSs who underwent PBT at the University of Tsukuba Hospital during the period from 1984 to 2020. Scores from 41 CCSs who did not undergo PBT (noPBT-CCSs) and from the general population were used for comparison.

resultsIn total, 110 individuals who underwent PBT participated in the study. Among them, 40 individuals were longitudinally analyzed. The range of change in the scores was significantly greater in the CCSs whose initial scores were low. Although the comorbidity levels were more severe, HRQoL tended to be better in the PBT-CCSs than in the noPBT-CCSs with central nervous system (CNS) or solid tumors, respectively. When compared with the general population, the psychosocial health summary scores and its components were not different in the noPBT-CNS-CCSs. On the other hand, the psychosocial health summary scores and/or at least one of the scores of emotional, social, and school functioning were significantly higher in the other CCSs groups.

conclusionsThe HRQoL scores of CCSs with low initial scores can be greatly changed over time. Appropriate psychosocial support for this population is warranted. PBT may avoid reduction in HRQoL in terms of the psychosocial functioning of CCSs with CNS tumors.

Indexed as

Cancer SurvivorsCentral Nervous System NeoplasmsNeoplasmsProton TherapyChildHumansQuality of LifeSurvivorsChildhood cancerEuroQoLHealth-related quality of lifeLong-term comorbidityPedsQLProton beam therapy

Identifiers

PMID37209157
OpenAlexW4377140266

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.