Evidence map›Paper›PMID 37208914›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

Development of a primate model to evaluate the effects of ketamine and surgical stress on the neonatal brain.

Cheng Wang, Adnan Bhutta, Xuan Zhang, Fang Liu, Shuliang Liu, Leah E Latham, John C Talpos, Tucker A Patterson, William Slikker

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Ketamine, an Old-New Drug: Uses and Abuses.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Cheng WangDivision of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration (FDA), Jefferson, AR 72079, USA.ORCID 0000-0002-8315-6232
Adnan BhuttaUniversity of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0003-3362-5835
Xuan ZhangDivision of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration (FDA), Jefferson, AR 72079, USA.
Fang LiuDivision of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration (FDA), Jefferson, AR 72079, USA.ORCID 0000-0002-4568-3859
Shuliang LiuDivision of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration (FDA), Jefferson, AR 72079, USA.
Leah E LathamDivision of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration (FDA), Jefferson, AR 72079, USA.
John C TalposDivision of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration (FDA), Jefferson, AR 72079, USA.
Tucker A PattersonOffice of Research, National Center for Toxicological Research, Food and Drug Administration (FDA), Jefferson, AR 72079, USA.
William SlikkerRetired.ORCID 0000-0002-9616-9462
National Center for Toxicological Research · USRiley Hospital for Children · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With advances in pediatric and obstetric surgery, pediatric patients are subject to complex procedures under general anesthesia. The effects of anesthetic exposure on the developing brain may be confounded by several factors including pre-existing disorders and surgery-induced stress. Ketamine, a noncompetitive

Indexed as

AnestheticsKetamineAnimalsAnimals, NewbornBrainPrimatesAnestheticsKetamineanesthesiaBraindevelopmentalneuroscienceneurotoxicologysurgery

Identifiers

PMID37208914
PMCPMC10350805
OpenAlexW4377139998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.