Evidence map›Paper›PMID 37208649›Full record

ArticleBMC public health2023

Exploring the factors contributing to low vaccination uptake for nationally recommended routine childhood and adolescent vaccines in Kenya.

Tene-Alima Essoh, Gbadebo Collins Adeyanju, Abdu A Adamu, Haoua Tall, Aristide Aplogan, Collins Tabu

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In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tene-Alima EssohAgence de Médecine Préventive (AMP) Afrique, Cote d'Ivoire, Abidjan, Côte d'Ivoire.
Gbadebo Collins AdeyanjuCenter for Empirical Research in Economics and Behavioral Science (CEREB), University of Erfurt, Erfurt, Germany. gbadebo.adeyanju@uni-erfurt.de.ORCID 0000-0002-5398-0183
Abdu A AdamuSouth African Medical Research Council, Cochrane South Africa, Cape Town, South Africa.
Haoua TallAgence de Médecine Préventive (AMP) Afrique, Cote d'Ivoire, Abidjan, Côte d'Ivoire.
Aristide AploganAgence de Médecine Préventive (AMP) Afrique, Cote d'Ivoire, Abidjan, Côte d'Ivoire.
Collins TabuKenya Medical Research Institute (KEMRI), Welcome trust, Nairobi, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaccination remains the most effective means of reducing the burden of infectious disease among children. It is estimated to prevent between two to three million child deaths annually. However, despite being a successful intervention, basic vaccination coverage remains below the target. About 20 million infants are either under or not fully vaccinated, most of whom are in Sub-Saharan Africa region. In Kenya, the coverage is even lower at 83% than the global average of 86%. The objective of this study is to explore the factors that contribute to low demand or vaccine hesitancy for childhood and adolescent vaccines in Kenya.

methodsThe study used qualitative research design. Key Informant Interviews (KII) was used to obtain information from national and county-level key stakeholders. In-depth Interviews (IDI) was done to collect opinions of caregivers of children 0-23 months and adolescent girls eligible for immunization, and Human papillomavirus (HPV) vaccine respectively. The data was collected at the national level and counties such as Kilifi, Turkana, Nairobi and Kitui. The data was analyzed using thematic content approach. A total of 41 national and county-level immunization officials and caregivers formed the sample.

resultsInsufficient knowledge about vaccines, vaccine supply issues, frequent healthcare worker's industrial action, poverty, religious beliefs, inadequate vaccination campaigns, distance to vaccination centers, were identified as factors driving low demand or vaccine hesitancy against routine childhood immunization. While factors driving low uptake of the newly introduced HPV vaccine were reported to include misinformation about the vaccine, rumors that the vaccine is a form of female contraception, the suspicion that the vaccine is free and available only to girls, poor knowledge of cervical cancer and benefits of HPV vaccine.

conclusionsRural community sensitization on both routine childhood immunization and HPV vaccine should be key activities post COVID-19 pandemic. Likewise, the use of mainstream and social media outreaches, and vaccine champions could help reduce vaccine hesitancy. The findings are invaluable for informing design of context-specific interventions by national and county-level immunization stakeholders. Further studies on the relationship between attitude towards new vaccines and connection to vaccine hesitancy is necessary.

Indexed as

COVID-19Papillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsAdolescentChildFemaleHealth Knowledge, Attitudes, PracticeHumansInfantKenyaPandemicsVaccinationPapillomavirus VaccinesAdolescent girlsGirlsHPV vaccineHuman papillomavirusImmunizationInfectious diseasesLow uptakeVaccinationVaccine demandVaccine hesitancyWomen

Identifiers

PMID37208649
PMCPMC10197028

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.