Evidence map›Paper›PMID 37208583›Full record

ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2023

Brain D2-Like Dopamine Receptor Distribution in Rats with Different Types of Genetic Epilepsy.

E T Tsyba, L M Birioukova, I S Midzyanovskaya, N M Surina, K R Abbasova

Abstract read
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In one paragraph

Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

E T TsybaBiological Faculty, Moscow State University, Moscow, Russia. evgeniya.tsyba@mail.ru.
L M BirioukovaInstitute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia.
I S MidzyanovskayaInstitute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia.
N M SurinaBiological Faculty, Moscow State University, Moscow, Russia.
K R AbbasovaBiological Faculty, Moscow State University, Moscow, Russia.
Lomonosov Moscow State University · RUInstitute of Higher Nervous Activity and Neurophysiology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distribution of the D2-like dopamine receptor (D2DR) in the cortex and striatum was compared between rats with absence, audiogenic, or combined genetically determined epilepsy and normal Wistar rats by autoradiography. A significantly lower D2DR binding density was observed in the dorsal and ventrolateral aspects of the nucleus accumbens in epileptic vs. non-epileptic rats. Rats with audiogenic epilepsy additionally showed a higher D2DR density in the dorsal striatum and motor and somatosensory cortex and a lower D2DR density in the ventrolateral part of the nucleus accumbens. The findings indicated that a common neuronal circuit is involved in the pathogenesis of both convulsive and nonconvulsive forms of generalized epilepsy.

Indexed as

BrainEpilepsy, ReflexAnimalsDisease Models, AnimalDopamineRatsRats, Inbred StrainsRats, WistarReceptors, Dopamine D2DopamineReceptors, Dopamine D2absence epilepsyaudiogenic epilepsyautoradiographydopamineKMneurotransmitterWAG/Rij

Identifiers

PMID37208583
OpenAlexW4377091599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.