Evidence map›Paper›PMID 37208096›Full record

ReviewJournal of hepatology2023

Evaluation of recipients with significant comorbidity - Patients with cardiovascular disease.

Emmanuel A Tsochatzis, Kymberly D Watt, Lisa B VanWagner, Elizabeth C Verna, Annalisa Berzigotti

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. New Scenarios in Liver Transplantation for Hepatocellular Carcinoma.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Emmanuel A TsochatzisUCL Institute for Liver and Digestive Health, Royal Free Campus, London, UK; Sheila Sherlock Liver Unit, Royal Free Hospital, London, UK. Electronic address: e.tsochatzis@ucl.ac.uk.
Kymberly D WattDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Lisa B VanWagnerDivision of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Elizabeth C VernaCenter for Liver Disease and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.
Annalisa BerzigottiDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Columbia University Irving Medical Center · USMayo Clinic in Arizona · USThe Royal Free Hospital · GBThe University of Texas Southwestern Medical Center · USUniversity of Bern · CH

Funding

Blood pressure as a modifiable risk factor for cardiovascular events in liver transplant recipientsR56HL155093 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI VANWAGNER, LISA B · 2021 to 2021
$774k
NHLBI NIH HHS R56 HL155093
6 · The paper itself

Abstract

Liver transplant(ation) (LT) is the most effective treatment for patients with decompensated liver disease. The increasing prevalence of obesity and type 2 diabetes and the growing number of patients with non-alcoholic fatty liver disease being evaluated for LT, have resulted in a greater proportion of LT candidates presenting with a higher risk of cardiovascular disease. As cardiovascular disease is a major cause of morbidity and mortality after LT, a thorough cardiovascular evaluation pre-LT is crucial. In this review, we discuss the latest evidence on the cardiovascular evaluation of LT candidates and we focus on the most prevalent conditions, namely ischaemic heart disease, atrial fibrillation and other arrhythmias, valvular heart disease, and cardiomyopathies. LT candidates undergo an electrocardiogram, a resting transthoracic echocardiography and an assessment of their cardiopulmonary functional ability as part of their standardised pre-LT work-up. Further diagnostic work-up is undertaken based on the results of the baseline evaluation and may include a coronary computed tomography angiography in patients with cardiovascular risk factors. The evaluation of potential LT candidates for cardiovascular disease requires a multidisciplinary approach, with input from anaesthetists, cardiologists, hepatologists and transplant surgeons.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Non-alcoholic Fatty Liver DiseaseComorbidityHumansRisk Factorscardiomyopathycardiopulmonary reservecirrhosisischaemic heart diseaseliver transplantationMELDNAFLDtype II diabetes

Identifiers

PMID37208096
PMCPMC11856630
OpenAlexW4376870737

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.