ReviewFrontiers in aging neuroscience2023
The association between stress, emotional states, and tinnitus: a mini-review.
Review in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 62 citations in OpenAlex.
- The Effect of 4-7-8 Breathing Exercise Technique on Tinnitus Handicap, Psychological Factors, and Sleep Quality in Tinnitus Patients: A Randomized Controlled Study.Brain and behavior · 2026Trial
- Photobiomodulation with near-infrared laser for tinnitus management: preliminary animal experiments and randomized clinical trials.Lasers in medical science · 2024Trial
- Audiologic Characteristics of Military Service Members and Veterans With and Without Tinnitus and Comorbid Posttraumatic Stress Disorder.American journal of audiology · 2026Article
- Increased prevalence of depressive symptoms and stress in patients with chronic bothersome tinnitus during the COVID-19 pandemic.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Impact of Education, Sex, and Residence on Tinnitus Distress, Depression, and Anxiety.Audiology research · 2026Article
- Tinnitus and Reactions to Tinnitus: A Cross-Sectional Survey Across Different Tinnitus Durations.Audiology research · 2026Article
- Influence of Hearing Loss on the Efficacy of Customized Music Therapy in Patients With Chronic Tinnitus.World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Tinnitus severity and chronicity in relation to hearing loss: a population-based study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Acupuncture Therapy in Tinnitus Using Single Needle Through Multiple Points Technique TE21-SI19-GB2 and GB3-SI19: A Case Report.Medical acupuncture · 2026Article
- Association Between Morning Blood Pressure Surge and Tinnitus in Hypertensive Patients: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Integrating the Sensation-Emotion-Cognition (SEC) Model into Tinnitus Care: A Preliminary Exploratory Study of a Comprehensive Tinnitus Management Protocol.Audiology research · 2026Article
- A primary auditory cortex-anterior cingulate cortex circuit underlying cross-modal visceral pain modulation.Nature communications · 2026Article
- Phantom Arm Pain and Tinnitus in a Patient with ST-Segment Elevation Myocardial Infarction: A Case Report.Clinical practice and cases in emergency medicine · 2026Article
- Association between combined occupational exposure to coal dust and noise and high-frequency hearing loss among workers: a cross-sectional study.Frontiers in public health · 2026Article
- Clinical investigation protocol for tinnitus (CIP-t): development and validation of an instrument.CoDAS · 2026Article
- Psychiatric Comorbidity in Chronic Tinnitus: Depression and Anxiety in an Otolaryngology Outpatient Cohort.Neuropsychiatric disease and treatment · 2026Article
- Prevalence and associated risk factors of tinnitus among Palestinian adolescents aged 15-18: A cross-sectional study.PloS one · 2026Article
- Beyond the auditory: anxiety bridges sleep disturbances and depressive symptoms to tinnitus handicap.Frontiers in psychiatry · 2026Article
- Tinnitus and occupational noise exposure among informal generator technicians in Nigeria: A pilot cohort study.PLOS global public health · 2026Article
- Breathing Rate as a Marker for Noise-Induced Stress in Guinea Pigs.Brain sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extensive literature supporting the view of tinnitus induced stress in patients is available. However, limited evidence has been produced studying the opposite, that is, does stress cause tinnitus? The hypothalamus pituitary adrenal axis, one of the main neuroendocrine systems involved in stress response, is commonly disturbed in tinnitus patients. Patients with chronic tinnitus have been shown to develop abnormal responses to psycho-social stress, where the hypothalamus pituitary adrenal axis response is weaker and delayed, suggesting chronic stress contributes to the development of chronic tinnitus. The sympathetic branch of the autonomic nervous system also plays a major role in stress response and its chronic hyperactivity seems to be involved in developing tinnitus. Psycho-social stress has been shown to share the same probability of developing tinnitus as occupational noise and contributes to worsening tinnitus. Additionally, exposure to high stress levels and occupational noise doubles the likelihood of developing tinnitus. Interestingly, short-term stress has been shown to protect the cochlea in animals, but chronic stress exposure has negative consequences. Emotional stress also worsens pre-existing tinnitus and is identified as an important indicator of tinnitus severity. Although there is limited body of literature, stress does seem to play a vital role in the development of tinnitus. This review aims to highlight the association between stress, emotional states, and the development of tinnitus while also addressing the neural and hormonal pathways involved.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.