Evidence map›Paper›PMID 37207012›Full record

ArticleThe International journal of angiology : official publication of the International College of Angiology, Inc2023

Low-Dose Alteplase versus Conventional Anticoagulation to treat Submassive Pulmonary Embolism in Hispanic Patients.

Emily Zientek, Kelsey Talkington, Joshua Gardner, Yi Guo, Debabrata Mukherjee, Manu Rajachandran, Tariq S Siddiqui, Nils P Nickel

Open access · greenAbstract read
In one paragraph

Article in The International journal of angiology : official publication of the International College of Angiology, Inc, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Prognostic Value of Right Ventricular Echocardiography on Mortality in Intermediate-Risk Hispanic Patients with Acute Pulmonary Embolism.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emily ZientekPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas.
Kelsey TalkingtonPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas.
Joshua GardnerPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas.
Yi GuoDepartment of Pharmacy, Clinical Pharmacy Services, University Medical Center of El Paso, El Paso, Texas.
Debabrata MukherjeePaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas.ORCID 0000-0002-5131-3694
Manu RajachandranPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas.
Tariq S SiddiquiPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas.
Nils P NickelPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas.
Texas Tech University · USUniversity Medical Center of El Paso · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of low-dose tissue plasminogen activator (tPA) in Hispanic patients with submassive pulmonary embolism (PE) is understudied. The purpose of this study is to explore the use of low-dose tPA in Hispanic patients with submissive PE compared with counterparts that received heparin alone. We retrospectively analyzed a single-center registry of patients with acute PE between 2016 and 2022. Out of 72 patients admitted for acute PE and cor pulmonale, we identified six patients that were treated with conventional anticoagulation (heparin alone) and six patients who received low-dose tPA (and heparin afterward). We analyzed if low-dose tPA was associated with differences in length of stay (LOS) and bleeding complications. Both groups were similar in regard to age, gender, and PE severity (based on Pulmonary Embolism Severity Index scores). Mean total LOS for the low-dose tPA group was 5.3 days, compared with 7.3 days in the heparin group (

Indexed as

anticoagulationhemodynamicsHispaniclength of staylow-dose alteplasepulmonary embolismtissue plasminogen activator

Identifiers

PMID37207012
PMCPMC10191688
OpenAlexW4310646721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.