ArticleFrontiers in public health2023
Nitrous oxide: a unique official French addictovigilance national survey.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Rapid decline of elevated homocysteine level in nitrous oxide use.Scientific reports · 2026Article
- Inclusive approaches to research and healthcare for nitrous oxide users: lessons from a longitudinal study.BMJ neurology open · 2026Article
- Social determinants of health in recreational nitrous oxide use: a narrative review.BMJ public health · 2026Review
- Nitrous Oxide Sourcing, Use and Harms: Insights From Australians Who Use Ecstasy/MDMA and Other Illicit Stimulants.Drug and alcohol review · 2025Article
- Contribution of Addictovigilance data to assess adverse-events linked to psychoactive substances in children and adolescents.British journal of clinical pharmacology · 2025Article
- SONOPS Multicentre Cross-Sectional Study: Study of the Nitrous Oxide Perception and Use in French Dental Students.International dental journal · 2025Article
- Rare but relevant: Nitrous oxide and peripheral neurotoxicity, what do we know?Addiction (Abingdon, England) · 2025Review
- Recreational nitrous oxide use in France in 2022: Results from a nationwide representative sample of adults.Drug and alcohol review · 2025Article
- Cerebral Venous Thrombosis and Nitrous Oxide Intoxication: Report of Two Cases and Review of the Literature.Brain and behavior · 2025Review
- First episode of catatonia followed by a psychotic episode related to chronic nitrous oxide use: A case report.Drug and alcohol review · 2025Article
- Sex/gender differences in spontaneous reports to a French Addictovigilance centre.Archives of women's mental health · 2025Article
- Right iliac deep vein thrombosis and pulmonary embolism associated with recreational nitrous oxide: a case report.International journal of emergency medicine · 2024Article
- Marked increase in severe neurological disorders after nitrous oxide abuse: a retrospective study in the Greater Paris area.Journal of neurology · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Nitrous oxide has become over the last few years a public health problem in many countries. France has a dedicated health monitoring system dedicated to the surveillance of the abuse, dependence and consequences associated with the use of psychoactive substances coordinated by the French National Agency for the Safety of Medicines and Health Products.We present the French national survey of nitrous oxide. Materials and methods: We analyzed all the cases with nitrous oxide from 2012 to 2021: number of notifications, characteristics of the subjects and consumption, consequences reported and their evolutions over time. In addition, we have made a special focus on the four main complications reported. Results: A total of 525 cases were received with an exponential increase since 2019. We observed changes in the characteristics of the notifications with an increase in the proportion of women [42.7% in 2021 vs. 30.8% in 2020 ( Discussion: The combination of high availability, varied effects from euphoria to relief of discomfort in a stressful global pandemic context and the development of dependence could explain the rapid growth of consumption and the seriousness of the cases.It must now be taken into account that (i) Substance use disorders are associated with nitrous oxide consumption; (ii) clinicians must consider "nitrous oxide" in young subjects presenting different types of manifestations; and (iii) stopping consumption is imperative and is the first treatment. In this context, an addictological assessment must also be carried out.
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