Evidence map›Paper›PMID 37206674›Full record

ArticlePrzeglad menopauzalny = Menopause review2023

Transplacental permeability of heavy metals in relation to newborn sex - evidence from the neurodevelopment project.

Giuseppe Giordano, Giuseppe Gullo, Marco Scaglione, Giovanni Buzzaccarini, Gaspare Cucinella, Domenico Gullo, Daniela Segreto, Vito Chiantera, Antonio Simone Laganà, Francesca Di Gaudio

Open access · goldAbstract read
In one paragraph

Article in Przeglad menopauzalny = Menopause review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Giuseppe Giordano *Neonatal Intensive Care Unit, Ospedali Riuniti "Villa Sofia - V. Cervello", Palermo, Italy.
Giuseppe Gullo *Department of Obstetrics and Gynaecology, "Villa Sofia - V. Cervello" Hospital, IVF UNIT, University of Palermo, Palermo, Italy.
Marco ScaglioneDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal-Child Sciences, University of Genoa, Genoa, Italy.
Giovanni BuzzaccariniObstetrics and Gynaecology Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Gaspare CucinellaDepartment of Obstetrics and Gynaecology, "Villa Sofia - V. Cervello" Hospital, IVF UNIT, University of Palermo, Palermo, Italy.
Domenico GulloTechnical Panel on Gender Medicine, Sicily Regional Health Service, Palermo, Italy.
Daniela SegretoTechnical Panel on Gender Medicine, Sicily Regional Health Service, Palermo, Italy.
Vito ChianteraUnit of Gynaecological Oncology, ARNAS "Civico - Di Cristina - Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.
Antonio Simone LaganàUnit of Gynaecological Oncology, ARNAS "Civico - Di Cristina - Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.
Francesca Di GaudioQuality Control and Chemical Risk (CQRC), Department PROMISE, University Hospital P. Giaccone, University of Palermo, Palermo, Italy.
Ospedale Vincenzo Cervello · ITDepartment of Health · ESUniversity of Genoa · ITUniversity of Palermo · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gender medicine is an innovative medical approach that studies how some biological variables are influenced by the male or female sex and gender. This issue is under debate because it characterizes the impact of tailored or individual medicine. In this scenario, the aim of this study is to study the correlation between heavy metal exposure and pathologies of neurodevelopment, according to the sex of newborns. In particular, this is an observational study under the name of the Neurosviluppo Project, involving 217 mother-child couples. Material and methods: The correlation with phenotype small for gestational age and congenital malformations were studied, but above all we focused on the pattern of placental permeability to heavy metals. Results: Our results are specifically related to foetal medicine and investigate the impact of foetal sex in transplacental metal exposure. Our results did not show any significant differences related to foetal sex in terms of congenital malformations or the other variables taken into consideration. However, because these conclusions are the first related to the gender medicine in transplacental foetal medicine, they could be a marked background for further studies. Conclusions: Considering the lack of data in literature regarding foetal sexual medicine and transplacental exposure, these study results are pioneering in terms of sexual foetal medicine. Possibly in the future, studies regarding the correlation between foetal sex and obstetrics outcomes will be performed.

Indexed as

gender medicinemetal exposuresex and gendersexual medicinetransplacental transport

Identifiers

PMID37206674
PMCPMC10189668
OpenAlexW4377142805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.