Evidence map›Paper›PMID 37206651›Full record

ReviewWorld journal of hepatology2023

Recent advances in recurrent hepatocellular carcinoma therapy.

Yu-Xue Gao, Qi-Qi Ning, Peng-Xiang Yang, Yuan-Yue Guan, Peng-Xiang Liu, Meng-Lu Liu, Lu-Xin Qiao, Xiang-Hua Guo, Tong-Wang Yang, De-Xi Chen

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yu-Xue GaoBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Qi-Qi NingBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Peng-Xiang YangBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Yuan-Yue GuanBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Peng-Xiang LiuBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Meng-Lu LiuBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Lu-Xin QiaoBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Xiang-Hua GuoBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Tong-Wang YangBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
De-Xi ChenBeijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
Beijing YouAn Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, accounting for 75%-85% of cases. Although treatments are given to cure early-stage HCC, up to 50%-70% of individuals may experience a relapse of the illness in the liver after 5 years. Research on the fundamental treatment modalities for recurrent HCC is moving significantly further. The precise selection of individuals for therapy strategies with established survival advantages is crucial to ensuring better outcomes. These strategies aim to minimize substantial morbidity, support good life quality, and enhance survival for patients with recurrent HCC. For individuals with recurring HCC after curative treatment, no approved therapeutic regimen is currently available. A recent study presented novel approaches, like immunotherapy and antiviral medication, to improve the prognosis of patients with recurring HCC with the apparent lack of data to guide the clinical treatment. The data supporting several neoadjuvant and adjuvant therapies for patients with recurring HCC are outlined in this review. We also discuss the potential for future clinical and translational investigations.

Indexed as

ImmunotherapyLiver transplantationNeoadjuvant and adjuvant therapyRecurrent hepatocellular carcinomaTherapy

Identifiers

PMID37206651
PMCPMC10190692
OpenAlexW4366541791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.