Evidence map›Paper›PMID 37206410›Full record

ArticleClinical and translational radiation oncology2023

The impact of palliative radiotherapy on health-related quality of life in patients with head and neck cancer - Results of a multicenter prospective cohort study.

Marie-Luise Weiss, Justus Domschikowski, David Krug, Mathias Sonnhoff, Mirko Nitsche, Wolfgang Hoffmann, Martina Becker-Schiebe, Felix Bock, Markus Hoffmann, Claudia Schmalz and 2 more

Abstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Real world outcomes of high dose hypo-fractionated radiation therapy for mucosal head and neck cancer in patients unsuitable for curative treatment.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marie-Luise WeissDepartment of Radiation Oncology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
Justus DomschikowskiDepartment of Radiation Oncology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
David KrugDepartment of Radiation Oncology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
Mathias SonnhoffCenter for Radiotherapy and Radiation Oncology, 28239 Bremen, Germany.
Mirko NitscheCenter for Radiotherapy and Radiation Oncology, 28239 Bremen, Germany.
Wolfgang HoffmannRadiotherapy & Radiation Oncology, Hospital Braunschweig, 38114 Braunschweig, Germany.
Martina Becker-SchiebeRadiotherapy & Radiation Oncology, Hospital Braunschweig, 38114 Braunschweig, Germany.
Felix BockDepartment of Radiotherapy, University of Rostock, 18059 Rostock, Germany.
Markus HoffmannDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Schleswig-Holstein Campus Kiel, Germany.
Claudia SchmalzDepartment of Radiation Oncology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
Jürgen DunstDepartment of Radiation Oncology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
Alexander FabianDepartment of Radiation Oncology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Palliative radiotherapy for patients with head and neck cancer can be used to alleviate symptoms. Only a few studies have investigated its impact on patient-reported outcomes (PRO). Therefore, we conducted a prospective multicenter observational study. The primary objective was to assess changes in health-related quality of life (HrQoL) per PRO. Methods: Eligibility criteria included i.) head and neck cancer and ii.) palliative radiotherapy indicated (EQD Results: From 06/2020 to 06/2022, 61 patients were screened and 21 patients were included. Due to death or decline in health-status, HrQoL data was available for 18 patients at the first fraction and for eight patients at t Conclusion: Despite low patient numbers and risk of selection bias, our study shows some evidence of a benefit from palliative radiotherapy for head and neck cancer as measured by PRO.German Clinical Trial Registry identifier: DRKS00021197.

Indexed as

Head and neck neoplasmsPalliative carePatient reported outcome measureQuality of lifeRadiotherapySigns and symptoms

Identifiers

PMID37206410
PMCPMC10189372

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.