Evidence map›Paper›PMID 37206374›Full record

ArticleCritical care explorations2023

Order Set Usage is Associated With Lower Hospital Mortality in Patients With Sepsis.

Christopher R Dale, Shelley Schoepflin Sanders, Shu Ching Chang, Omar Pandhair, Naomi G Diggs, Whitney Woodruff, David N Selander, Nicholas M Mark, Sarah Nurse, Mark Sullivan and 2 more

Abstract read
In one paragraph

Article in Critical care explorations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Standardizing the diagnosis of necrotizing enterocolitis in infants with congenital heart disease.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  2. Article
  3. Decreased racial disparities in sepsis mortality after an order set-driven initiative: An analysis of 8151 patients.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christopher R DaleSwedish Health Services, Seattle, WA.
Shelley Schoepflin SandersProvidence St. Vincent Medical Center, Portland, OR.
Shu Ching ChangCenter for Cardiovascular Analytics, Research and Data Science (CARDS), Providence Heart Institute, Portland, OR.
Omar PandhairProvidence St. Vincent Medical Center, Portland, OR.
Naomi G DiggsSwedish Health Services, Seattle, WA.
Whitney WoodruffProvidence, Renton, WA.
David N SelanderSwedish Health Services, Seattle, WA.
Nicholas M MarkSwedish Health Services, Seattle, WA.
Sarah NurseProvidence, Renton, WA.
Mark SullivanSwedish Health Services, Seattle, WA.
Liga MezaraupsProvidence, Renton, WA.
D Shane O'MahonySwedish Health Services, Seattle, WA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Surviving Sepsis Campaign recommends standard operating procedures for patients with sepsis. Real-world evidence about sepsis order set implementation is limited.

objectivesTo estimate the effect of sepsis order set usage on hospital mortality.

designRetrospective cohort study. SETTING AND

participantsFifty-four acute care hospitals in the United States from December 1, 2020 to November 30, 2022 involving 104,662 patients hospitalized for sepsis. MAIN OUTCOMES AND MEASURES: Hospital mortality.

resultsThe sepsis order set was used in 58,091 (55.5%) patients with sepsis. Initial mean sequential organ failure assessment score was 0.3 lower in patients for whom the order set was used than in those for whom it was not used (2.9 sd [2.8] vs 3.2 [3.1], CONCLUSIONS AND RELEVANCE: In a cohort of patients hospitalized with sepsis, order set use was independently associated with lower hospital mortality. Order sets can impact large-scale quality improvement efforts.

Indexed as

clinical decision supporthealth servicesorder setquality improvementsepsis

Identifiers

PMID37206374
PMCPMC10191554

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.