ArticleBiomaterials translational2023
Effect of radiation sterilisation on the structure and antibacterial properties of antimicrobial peptides.
Article in Biomaterials translational, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 8 citations in OpenAlex.
- A Chemiluminescence-Activated Photodynamic Platform to Penetrate MRSA Biofilms and Counteract HSmall science · 2026Article
- Immunoregulatory electrospinning fiber mediates Macrophage energy metabolism reprogramming to promote burn wound healing.Materials today. Bio · 2025Article
- Dual-functional probiotic hydrogel with puerarin integration for microbiota-neuroimmune regulation in antibiotic-free periodontitis therapy.Bioactive materials · 2025Article
- Membrane biomimetic nanoenzyme-incorporated hybrid glycyrrhizic acid hydrogel for precise mitochondrial ROS scavenging for osteoarthritis treatment.Materials today. Bio · 2025Article
- "Disguise strategy" to bacteria: A multifunctional hydrogel with bacteria-targeting and photothermal conversion properties for the repair of infectious bone defects.Bioactive materials · 2025Article
- Binary Doping of Strontium-Magnesium to Bioactive Glasses to Enhance Antibacterial and Osteogenic Effects.ACS omega · 2025Article
- A multifunctional composite scaffold responds to microenvironment and guides osteogenesis for the repair of infected bone defects.Journal of nanobiotechnology · 2024Article
- Medical Device-Associated Healthcare Infections: Sterilization and the Potential of Novel Biological Approaches to Ensure Patient Safety.International journal of molecular sciences · 2023Review
- The emergence of AI tools in scientific writing and research.Biomaterials translational · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial peptides (AMPs) have recently been exploited to fabricate anti-infective medical devices due to their biocompatibility and ability to combat multidrug-resistant bacteria. Modern medical devices should be thoroughly sterilised before use to avoid cross-infection and disease transmission, consequently it is essential to evaluate whether AMPs withstand the sterilisation process or not. In this study, the effect of radiation sterilisation on the structure and properties of AMPs was explored. Fourteen AMPs formed from different monomers with different topologies were synthesised by ring-opening polymerisation of N-carboxyanhydrides. The results of solubility testing showed that the star-shaped AMPs changed from water-soluble to water-insoluble after irradiation, while the solubility of linear AMPs remained unchanged. Matrix-assisted laser desorption/ionisation time of flight mass spectrometry showed that the molecular weight of the linear AMPs underwent minimal changes after irradiation. The results of minimum inhibitory concentration assay also illustrated that radiation sterilisation had little effect on the antibacterial properties of the linear AMPs. Therefore, radiation sterilisation may be a feasible method for the sterilisation of AMPs, which have promising commercial applications in medical devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.