Evidence map›Paper›PMID 37206248›Full record

ArticleBioengineering & translational medicine2023

Genetically engineered pair of cells for serological testing and its application for SARS-CoV-2.

Marvin A Ssemadaali, Juan Arredondo, Elise A Buser, Sherri Newmyer, Harikrishnan Radhakrishnan, Harold S Javitz, Satya Dandekar, Parijat Bhatnagar

Open access · goldAbstract read
In one paragraph

Article in Bioengineering & translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Syngeneic CAR T cells engineered for persistent delivery of desired proteins.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  3. Engineered CD4 T cells for in vivo delivery of therapeutic proteins.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marvin A SsemadaaliBiosciences Division SRI International Menlo Park California 94025 United States.ORCID https://orcid.org/0000-0002-6869-8025
Juan ArredondoMedical Microbiology and Immunology University of California Davis Davis California 95616 United States.
Elise A BuserMedical Microbiology and Immunology University of California Davis Davis California 95616 United States.
Sherri NewmyerBiosciences Division SRI International Menlo Park California 94025 United States.ORCID https://orcid.org/0000-0003-1039-5416
Harikrishnan RadhakrishnanBiosciences Division SRI International Menlo Park California 94025 United States.ORCID https://orcid.org/0000-0002-5435-4520
Harold S JavitzEducation Division SRI International Menlo Park California 94025 United States.ORCID https://orcid.org/0000-0002-6370-174X
Satya DandekarMedical Microbiology and Immunology University of California Davis Davis California 95616 United States.
Parijat BhatnagarBiosciences Division SRI International Menlo Park California 94025 United States.ORCID https://orcid.org/0000-0001-9783-3364
SRI International · USUniversity of California Davis Medical Center · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
Self-assembled therapeutics with spatiotemporal resolutionDP2EB024245 · NIBIB · SRI INTERNATIONAL · PI BHATNAGAR, PARIJAT · 2016 to 2016
$3.0M
T-cell Biofactories for targeting extracellular matrixR33CA247739 · NCI · SRI INTERNATIONAL · PI BHATNAGAR, PARIJAT · 2020 to 2020
$1.6M
T-cell Biofactories for targeting interstitial fluid pressureR21CA236640 · NCI · SRI INTERNATIONAL · PI BHATNAGAR, PARIJAT · 2019 to 2022
$818k
NCI NIH HHS P30 CA093373NCI NIH HHS R21 CA236640NCI NIH HHS R33 CA247739NIBIB NIH HHS DP2 EB024245
6 · The paper itself

Abstract

We have developed a serology test platform for identifying individuals with prior exposure to specific viral infections and provide data to help reduce public health risks. The serology test composed of a pair of cell lines engineered to express either a viral envelop protein (Target Cell) or a receptor to recognize the Fc region of an antibody (Reporter Cell), that is,

Indexed as

cell‐based sensorscell engineeringCOVID‐19 diagnosticsserology testsynthetic biology

Identifiers

PMID37206248
PMCPMC10189431
OpenAlexW4360857224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.