Evidence map›Paper›PMID 37206028›Full record

ReviewHeliyon2023

Unravelling the potential of insects for medicinal purposes - A comprehensive review.

Shahida Anusha Siddiqui, Chujun Li, Owusu Fordjour Aidoo, Ito Fernando, Moawiya A Haddad, Jorge A M Pereira, Andrey Blinov, Andrey Golik, José S Câmara

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Toxicology research · 2026
    Article
  4. Article
  5. Protective Effect ofFood science & nutrition · 2026
    Article
  6. Article
  7. Article
  8. Peptide Fractions Extracted from the Hemolymph ofInternational journal of molecular sciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 6 countries.

Shahida Anusha SiddiquiTechnical University of Munich Campus Straubing for Biotechnology and Sustainability, Essigberg 3, 94315 Straubing, Germany.
Chujun LiGuangzhou Unique Biotechnology Co., Ltd, 510663, Guangzhou, China.
Owusu Fordjour AidooDepartment of Biological, Physical and Mathematical Sciences, University of Environment and Sustainable Development, 00233, Somanya, Ghana.
Ito FernandoDepartment of Plant Pest and Diseases, Faculty of Agriculture, Universitas Brawijaya, Malang, 65145, East Java, Indonesia.
Moawiya A HaddadDepartment of Nutrition and Food Processing, Faculty of Agricultural Technology, Al-Balqa Applied University, 19117, Al-Salt, Jordan.
Jorge A M PereiraCQM - Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal.
Andrey BlinovNorth Caucasus Federal University, Pushkina Street 1, 355009, Stavropol, Russia.
Andrey GolikNorth Caucasus Federal University, Pushkina Street 1, 355009, Stavropol, Russia.
José S CâmaraCQM - Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal.
North-Caucasus Federal University · RUUniversidade da Madeira · PTAl-Balqa Applied University · JOGerman Institute of Food Technologies · DESun Yat-sen University · CNUniversity of Brawijaya · IDUniversity of Environment and Sustainable Development

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Entomotherapy, the use of insects for medicinal purposes, has been practised for centuries in many countries around the world. More than 2100 edible insect species are eaten by humans, but little is known about the possibility of using these insects as a promising alternative to traditional pharmaceuticals for treating diseases. This review offers a fundamental understanding of the therapeutic applications of insects and how they might be used in medicine. In this review, 235 insect species from 15 orders are reported to be used as medicine. Hymenoptera contains the largest medicinal insect species, followed by Coleoptera, Orthoptera, Lepidoptera, and Blattodea. Scientists have examined and validated the potential uses of insects along with their products and by-products in treating various diseases, and records show that they are primarily used to treat digestive and skin disorders. Insects are known to be rich sources of bioactive compounds, explaining their therapeutic features such as anti-inflammatory, antimicrobial, antiviral, and so on. Challenges associated with the consumption of insects (entomophagy) and their therapeutic uses include regulation barriers and consumer acceptance. Moreover, the overexploitation of medicinal insects in their natural habitat has led to a population crisis, thus necessitating the investigation and development of their mass-rearing procedure. Lastly, this review suggests potential directions for developing insects used in medicine and offers advice for scientists interested in entomotherapy. In future, entomotherapy may become a sustainable and cost-effective solution for treating various ailments and has the potential to revolutionize modern medicine.

Indexed as

Consumer acceptanceDiseasesEdible insectEntomophagyEntomotherapyMass rearingMedicine

Identifiers

PMID37206028
PMCPMC10189416
OpenAlexW4367301060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.