ArticleHeliyon2023
Anatomical landscape of oral squamous cell carcinoma: A single cancer center study in UAE.
Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Novel patient-derived tongue squamous cell carcinoma cell lines from non-smokers: 3D and in vivo models for drug response studies.Medical oncology (Northwood, London, England) · 2026Article
- Integrated analysis identifies CCNA2 as a candidate diagnostic and prognostic biomarker in oral tongue squamous cell carcinoma.Journal of applied oral science : revista FOB · 2026Article
- Frequency of Oral Squamous Cell Carcinoma in Two Public Hospitals in Peru: A Ten-Year Retrospective Study.Oral health & preventive dentistry · 2025Article
- Potential antisense oligonucleotide targeting LINC00673 on proliferation and apoptosis in tongue squamous cell carcinoma.Journal of Taibah University Medical Sciences · 2025Article
- Comparison of level of circulating tumor DNA between oral squamous cell carcinoma and healthy controls: a case control study.BMC oral health · 2025Article
- PADI4 expression in baseline circulating tumour cells acts as a prognostic biomarker in oral squamous cell carcinoma.The journal of liquid biopsy · 2025Article
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- Factors associated with the survival of oral cavity cancer patients: a single institution experience from Karachi, Pakistan.BMC oral health · 2024Article
- NTRK Gene Expression Analysis in Oral Squamous Cell Carcinoma Mexican Population.Dentistry journal · 2024Article
- Prognostic importance of modified geriatric nutritional risk index in oral cavity squamous cell carcinoma.Scientific reports · 2024Article
- Squamous cell carcinoma initially occurring on the tongue dorsum: a case series report with molecular analysis.Diagnostic pathology · 2024Article
- Clinical outcomes and impact of prognostic factors in resectable oral cavity squamous cell carcinoma.Frontiers in oncology · 2024Article
- Prognostic factors analysis of patients with oral cavity squamous cell carcinoma.Brazilian journal of otorhinolaryngologyObservational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aimed to present demographic and clinicopathological aspects of OSCC identified in Pathology service in the UAE over a 13-year period and compare these findings to a cohort of 523 cases of Head and neck squamous cell carcinoma using the Cancer Genome Atlas's cBioPortal database (http://cbioportal.org). Material and methods: Histological examination of all hematoxylin and eosin-stained slides and assessment of all demographic and clinical information from laboratory records were performed on all OSCC diagnosed between 2005 and 2018. Results: Males made up 71.4% of the sample of 231 OSCCs that were evaluated. The patients' average age was 55.38 years. The two most prevalent afflicted sites were the anterior two-thirds of the tongue (57.6%) and the cheek (28.1%). The most prevalent site among smokers were the floor of mouth, cheek, and jaw bones. There was a link between tumor size and numerous anatomical subsites that was shown to be highly significant. OSCC in the FOM was associated with a 25% mortality rate. Patients with OSCC of the anterior tongue and cheek had the best prognosis, with only 15.7% and 15.3% of patients dying during follow-up. Conclusion: The present investigation found a correlation between the diverse clinicopathological characteristics of the various anatomical subsites in OSCC. Different anatomical subsites also displayed varying degrees of gene mutation.
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