Evidence map›Paper›PMID 37205881›Full record

ArticleJournal of conservative dentistry : JCD

Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste.

Mithra N Hegde, N Suchetha Kumari, Nireeksha Shetty, V Chaithra Lakshmi, Nidarsh Divakar Hegde, Nishmitha N Hegde, Jyoti Singh, Amit Sirdesai, Prasun Bandyopadhyay

Abstract read
In one paragraph

Article in Journal of conservative dentistry : JCD. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mithra N HegdeDepartment of Conservative Dentistry and Endodontics, A. B. Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India.
N Suchetha KumariDepartment of Biochemistry, Central Research Laboratory, KSHEMA, Mangalore, Karnataka, India.
Nireeksha ShettyDepartment of Conservative Dentistry and Endodontics, A. B. Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India.
V Chaithra LakshmiDepartment of Conservative Dentistry and Endodontics, A. B. Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India.
Nidarsh Divakar HegdeDepartment of Oral & Maxillofacial Surgery, Dental College Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India.
Nishmitha N HegdeDepartment of Conservative Dentistry and Endodontics, A. B. Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.
Jyoti SinghResearch Scientist, R & D, Dabur India Ltd, Sahibabad, Ghaziabad, Uttar Pradesh, India.
Amit SirdesaiResearch Scientist, R & D, Dabur India Ltd, Sahibabad, Ghaziabad, Uttar Pradesh, India.
Prasun BandyopadhyayGlobal VP Home & Personal Care, Dabur India Ltd, Sahibabad, Ghaziabad, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to study the effect of medicated toothpaste on oral health, a 6-month follow-up. Methods: Four hundred and twenty-seven participants were screened and followed up for 6 months. The intraoral examination was performed to record caries, gingival bleeding, and plaque index. Saliva collected was evaluated for pH, total antioxidant capacity (TAC), malondialdehyde (MDA), and Vitamin C level for 6 months, and data were analyzed. Results: On the usage of medicated toothpaste with herbal extract for 6 months, the salivary pH levels were increased, the interquartile range for plaque, and the gingival bleeding index decreased. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-free group of subgroup I was 174.8, 58.06, and 59.98, respectively, in subgroup II was 133.3, 52.08, and 58.51, and in subgroup III was 63.77, 45.11, and 47.77. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-active group of subgroup I was 136.62, 57.27, and 72.83, subgroup II was 108.59, 37.50, and 61.55, and in subgroup III was 35.62, 30.82, and 54.10, respectively. Conclusion: The salivary pH levels increased on the usage of medicated toothpaste with herbal extract; plaque and the gingival bleeding index scores were decreased. The salivary antioxidant defense was increased in individuals using medicated toothpaste with herbal extracts which signifies an improvement in overall oral health in the 6-month follow-up.

Indexed as

Dental cariesdental plaquefree radical scavengersgingivitisoral healthoxidative stress

Identifiers

PMID37205881
PMCPMC10190079

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.