Evidence map›Paper›PMID 37205767›Full record

ArticleScience immunology2023

Cytolytic CD8

David R Collins, Julia Hitschfel, Jonathan M Urbach, Geetha H Mylvaganam, Ngoc L Ly, Umar Arshad, Zachary J Racenet, Adrienne G Yanez, Thomas J Diefenbach, Bruce D Walker

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Renaissance of antiviral CD8Nature reviews. Immunology · 2026
    Review
  2. Article
  3. Review
  4. The HIV reservoir landscape in elite controllers.Current opinion in HIV and AIDS · 2026
    Review
  5. HIV controllers, lessons learnt from the lymphoid tissues.Current opinion in HIV and AIDS · 2026
    Review
  6. Article
  7. CD8Nature · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. CD8medRxiv : the preprint server for health sciences · 2025
    Article
  12. Roadmap for spatial transcriptomics of HIV in tissues.Current opinion in HIV and AIDS · 2025
    Review
  13. Therapeutic CD8Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. HIV controllers: hope for a functional cure.Frontiers in immunology · 2025
    Review
  18. Review
  19. Article
  20. Distinct SIV-specific CD8Nature immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

David R CollinsRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0001-7903-346X
Julia HitschfelRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0002-2198-4905
Jonathan M UrbachRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0003-0597-2848
Geetha H MylvaganamRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
Ngoc L LyRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
Umar ArshadRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0002-9671-8193
Zachary J RacenetRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0002-5299-3716
Adrienne G YanezRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0003-3346-9692
Thomas J DiefenbachRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0002-2798-5909
Bruce D WalkerRagon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.ORCID 0000-0001-6122-9245
Ragon Institute of MGH, MIT and Harvard · USHoward Hughes Medical Institute · USFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

Identification of neutralizing epitopes on SARS-CoV-2 spike for design of vaccines and small-molecule antiviralsUM1AI144462 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BURTON, DENNIS R. · 2019 to 2025
$201.6M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
Molecular networks of HIV-specific CD4 T cell help to B cellsR01AI118544 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WALKER, BRUCE D · 2015 to 2019
$2.2M
Understanding and Reversing T Cell Dysfunction to Control and Eliminate Persistent HIV ReservoirsR01AI149704 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WALKER, BRUCE D · 2020 to 2024
$2.1M
Modulating T Cell Activation to Combat HIV PersistenceDP2AI184606 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI David Randolph Collins · 2024 to 2026
$1.5M
Howard Hughes Medical InstituteNIAID NIH HHS DP2 AI184606NIAID NIH HHS L30 AI126472NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI118544NIAID NIH HHS R01 AI149704NIAID NIH HHS UM1 AI144462
6 · The paper itself

Abstract

Follicular CD8

Indexed as

CD8-Positive T-LymphocytesHIV InfectionsGerminal CenterHumansLymph NodesVirus Replication

Identifiers

PMID37205767
PMCPMC10231436
OpenAlexW4377088166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.