Evidence map›Paper›PMID 37205575›Full record

ArticlemedRxiv : the preprint server for health sciences2023

DeepPhe-CR: Natural Language Processing Software Services for Cancer Registrar Case Abstraction.

Harry Hochheiser, Sean Finan, Zhou Yuan, Eric B Durbin, Jong Cheol Jeong, Isaac Hands, David Rust, Ramakanth Kavuluru, Xiao-Cheng Wu, Jeremy L Warner and 1 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Harry HochheiserDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.
Sean FinanBoston Childrens' Hospital, Boston, MA, USA and Harvard Medical School, Boston, MA, USA.
Zhou YuanDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.
Eric B DurbinKentucky Cancer Registry, Markey Cancer Center, Lexington, KY, USA.
Jong Cheol JeongDivision of Biomedical Informatics, College of Medicine, University of Kentucky, Lexington, KY, USA.
Isaac HandsKentucky Cancer Registry, Markey Cancer Center, Lexington, KY, USA.
David RustKentucky Cancer Registry, Markey Cancer Center, Lexington, KY, USA.
Ramakanth KavuluruDivision of Biomedical Informatics, College of Medicine, University of Kentucky, Lexington, KY, USA.
Xiao-Cheng WuLouisiana Cancer Registry, New Orleans, LA, USA.
Jeremy L WarnerLifespan Health System, Providence, RI, USA.
Guergana SavovaBoston Childrens' Hospital, Boston, MA, USA and Harvard Medical School, Boston, MA, USA.

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers · 2013 to 2026
$38.3M
Cancer Deep Phenotyping from Electronic Medical RecordsU24CA248010 · NCI · BOSTON CHILDREN'S HOSPITAL · PI HARRY S HOCHHEISER, GUERGANA K. SAVOVA · 2020 to 2026
$6.1M
Natural Language Processing Platform for Cancer SurveillanceUH3CA243120 · NCI · BOSTON CHILDREN'S HOSPITAL · PI DURBIN, ERIC B., HOCHHEISER, HARRY S · 2021 to 2023
$2.1M
NCI NIH HHS HHSN261201800013INCI NIH HHS P30 CA177558NCI NIH HHS U24 CA248010NCI NIH HHS UH3 CA243120
6 · The paper itself

Abstract

Objective: The manual extraction of case details from patient records for cancer surveillance efforts is a resource-intensive task. Natural Language Processing (NLP) techniques have been proposed for automating the identification of key details in clinical notes. Our goal was to develop NLP application programming interfaces (APIs) for integration into cancer registry data abstraction tools in a computer-assisted abstraction setting. Methods: We used cancer registry manual abstraction processes to guide the design of DeepPhe-CR, a web-based NLP service API. The coding of key variables was done through NLP methods validated using established workflows. A container-based implementation including the NLP wasdeveloped. Existing registry data abstraction software was modified to include results from DeepPhe-CR. An initial usability study with data registrars provided early validation of the feasibility of the DeepPhe-CR tools. Results: API calls support submission of single documents and summarization of cases across multiple documents. The container-based implementation uses a REST router to handle requests and support a graph database for storing results. NLP modules extract topography, histology, behavior, laterality, and grade at 0.79-1.00 F1 across common and rare cancer types (breast, prostate, lung, colorectal, ovary and pediatric brain) on data from two cancer registries. Usability study participants were able to use the tool effectively and expressed interest in adopting the tool. Discussion: Our DeepPhe-CR system provides a flexible architecture for building cancer-specific NLP tools directly into registrar workflows in a computer-assisted abstraction setting. Improving user interactions in client tools, may be needed to realize the potential of these approaches. DeepPhe-CR: https://deepphe.github.io/.

Indexed as

Application Programming InterfacesCancer InformaticsCancer RegistryData AbstractionNatural Language Processing

Identifiers

PMID37205575
PMCPMC10187451

What OpenQuestion holds

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LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.