Evidence map›Paper›PMID 37205495›Full record

ArticlebioRxiv : the preprint server for biology2023

Common Analysis of Direct RNA SequencinG CUrrently Leads to Misidentification of 5-Methylcytosine Modifications at GCU Motifs.

Kaylee J Watson, Robin E Bromley, Benjamin C Sparklin, Mark T Gasser, Tamanash Bhattacharya, Jarrett F Lebov, Tyonna Tyson, Laura E Teigen, Karen T Graf, Michelle Michalski and 5 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Kaylee J WatsonInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0009-0008-2288-5723
Robin E BromleyInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Benjamin C SparklinInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Mark T GasserInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-9396-4954
Tamanash BhattacharyaDepartment of Biology, Indiana University, Bloomington, IN, USA.
Jarrett F LebovInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Tyonna TysonInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Laura E TeigenDepartment of Biology, University of Wisconsin Oshkosh, Oshkosh, WI, USA.
Karen T GrafInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Michelle MichalskiDepartment of Biology, University of Wisconsin Oshkosh, Oshkosh, WI, USA.
Vincent M BrunoInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Amelia R I LindseyDepartment of Biology, Indiana University, Bloomington, IN, USA.ORCID 0000-0003-3354-7419
Richard W HardyDepartment of Biology, Indiana University, Bloomington, IN, USA.
Irene L G NewtonDepartment of Biology, Indiana University, Bloomington, IN, USA.
Julie C Dunning HotoppInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0003-3862-986X
University of Maryland, Baltimore · USIndiana University Bloomington · USUniversity of Wisconsin–Oshkosh · US

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RASKO, DAVID A · 2014 to 2023
$36.5M
Systems-Level Research in Microbial PathogenesisT32AI162579 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI NICHOLAS H CARBONETTI, Julie Dunning Hotopp · 2022 to 2026
$1.7M
NIAID NIH HHS T32 AI162579NIAID NIH HHS U19 AI110820
6 · The paper itself

Abstract

RNA modifications, such as méthylation, can be detected with Oxford Nanopore Technologies direct RNA sequencing. One commonly used tool for detecting 5-methylcytosine (m

Identifiers

PMID37205495
PMCPMC10187288
OpenAlexW4368370180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.