Evidence map›Paper›PMID 37204987›Full record

ArticleInternational statistical review = Revue internationale de statistique2022

A Legacy of EM Algorithms.

Kenneth Lange, Hua Zhou

Abstract read
In one paragraph

Article in International statistical review = Revue internationale de statistique, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Cornucopia of Maximum Likelihood Algorithms.The American statistician · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kenneth LangeDepartments of Computational Medicine, Human Genetics, and Statistics, University of California Los Angeles, Los Angeles, 90095-1766CA, USA.
Hua ZhouDepartments of Biostatistics and Computational Medicine, University of California Los Angeles, Los Angeles, 90095-1772CA, USA.ORCID 0000-0003-1320-7118

Funding

Genomics, GPUs, and Next Generation Computational StatisticsR01HG006139 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SOBEL, ERIC · 2011 to 2023
$5.1M
Modeling, Inference, and Optimization for Genomic and Biomedical Big DataR35GM141798 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LANGE, KENNETH L · 2021 to 2025
$2.7M
NHGRI NIH HHS R01 HG006139NIGMS NIH HHS R35 GM141798
6 · The paper itself

Abstract

Nan Laird has an enormous and growing impact on computational statistics. Her paper with Dempster and Rubin on the expectation-maximisation (EM) algorithm is the second most cited paper in statistics. Her papers and book on longitudinal modelling are nearly as impressive. In this brief survey, we revisit the derivation of some of her most useful algorithms from the perspective of the minorisation-maximisation (MM) principle. The MM principle generalises the EM principle and frees it from the shackles of missing data and conditional expectations. Instead, the focus shifts to the construction of surrogate functions via standard mathematical inequalities. The MM principle can deliver a classical EM algorithm with less fuss or an entirely new algorithm with a faster rate of convergence. In any case, the MM principle enriches our understanding of the EM principle and suggests new algorithms of considerable potential in high-dimensional settings where standard algorithms such as Newton's method and Fisher scoring falter.

Indexed as

EM algorithmlongitudinal data analysisMM algorithmvariance component model

Identifiers

PMID37204987
PMCPMC10191373

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.