Evidence map›Paper›PMID 37204940›Full record

ArticleInternational journal of methods in psychiatric research2023

Synchrony in psychotherapy: High physiological positive concordance predicts symptom reduction and negative concordance predicts symptom aggravation.

Clara C Gernert, Afton Nelson, Peter Falkai, Christine M Falter-Wagner

Abstract read
In one paragraph

Article in International journal of methods in psychiatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Heart rate synchrony as an objective biomarker in psychotherapy: a wearable-based pilot study.European archives of psychiatry and clinical neuroscience · 2026
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Clara C GernertDepartment of Psychiatry, Medical Faculty, LMU Munich, Munich, Germany.ORCID https://orcid.org/0000-0003-4931-3983
Afton NelsonDepartment of Psychiatry, Medical Faculty, LMU Munich, Munich, Germany.
Peter FalkaiDepartment of Psychiatry, Medical Faculty, LMU Munich, Munich, Germany.
Christine M Falter-WagnerDepartment of Psychiatry, Medical Faculty, LMU Munich, Munich, Germany.

Funding

FöFoLe-Programme 2018/2020
6 · The paper itself

Abstract

objectiveTherapeutic alliance is often considered as a predictor for therapeutic success. This study explored dyadic synchrony of skin conductance response (SCR) during naturalistic therapeutic interactions and investigated its potential as an objective biomarker for predicting therapy effectiveness.

methodsIn this proof-of-concept study, skin conductance from both dyad members was continuously measured via wristbands during psychotherapy. Patients and therapists completed post-session reports capturing their subjective appraisal of therapeutic alliance. Additionally, patients completed symptom questionnaires. Each therapeutic dyad was recorded twice in a follow-up design. The first session of the follow-up group was assessed for physiological synchrony (Single Session Index (SSI)). Therapy outcome was captured by the difference between symptom severity scores over time.

resultsSCR synchrony significantly predicted the outcome variable of change in patients' global severity index (GSI). High positive SCR concordance was linked to a reduction in patients' GSI, while negative or small positive SSI values were linked to an increase in patients' GSI.

conclusionThe results demonstrate the presence of SCR synchrony in clinical interactions. Skin conductance response synchrony was a significant predictor for change in patients' symptom severity index, emphasizing its potential as an objective biomarker in the context of evidence-based psychotherapy.

Indexed as

cognitive behavioural therapyinterpersonal synchronyobjective biomarkerspsychotherapy researchskin conductance

Identifiers

PMID37204940
PMCPMC10804325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.