Evidence map›Paper›PMID 37204614›Full record

ArticleInternational journal of colorectal disease2023

Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond.

Pasquale Scognamiglio, Anja Seeger, Matthias Reeh, Nathaniel Melling, Karl F Karstens, Thomas Rösch, Jakob R Izbicki, Marcus Kantowski, Michael Tachezy

Abstract read
In one paragraph

Article in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Endoscopic vacuum therapy.iGIE : innovation, investigation and insights · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pasquale ScognamiglioDepartment of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martini Str. 52, 20246, Hamburg, Germany. p.scognamiglio@uke.de.
Anja SeegerDepartment of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martini Str. 52, 20246, Hamburg, Germany.
Matthias ReehDepartment of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martini Str. 52, 20246, Hamburg, Germany.
Nathaniel MellingDepartment of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martini Str. 52, 20246, Hamburg, Germany.
Karl F KarstensDepartment of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martini Str. 52, 20246, Hamburg, Germany.
Thomas RöschClinic of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Jakob R IzbickiDepartment of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martini Str. 52, 20246, Hamburg, Germany.
Marcus Kantowski *Elisabethinum Medical Care Center, Hamburg, Germany.
Michael Tachezy *Department of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martini Str. 52, 20246, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe treatment of anastomotic leakage after left colorectal surgery remains challenging. Since its introduction, endoscopic negative pressure therapy (ENPT) has proven to be advantageous, reducing the necessity of surgical revision. The aim of our study is to present our experience with endoscopic treatment of colorectal leakages and to identify potential factors influencing treatment outcome.

methodsPatients who underwent endoscopic treatment of colorectal leakage were retrospectively analyzed. Primary endpoint was the healing rate and success of endoscopic therapy.

resultsWe identified 59 patients treated with ENPT between January 2009 and December 2019. The overall closure rate was 83%, whereas only 60% of the patients were successfully treated with ENPT and 23% needed further surgery. The time between diagnosis of leakage and uptake of endoscopic treatment did not influence the closure rate, but patients with chronic fistula (> 4 weeks) showed a significantly higher reoperation rate than those with an acute fistula (94% vs 6%, p = 0.01).

conclusionENPT is a successful treatment option for colorectal leakages, which appears to be more favorable when started early. Further studies are still needed to better describe its healing potential, but it deserves an integral role in the interdisciplinary treatment of anastomotic leakages.

Indexed as

Colorectal NeoplasmsColorectal SurgeryFistulaNegative-Pressure Wound TherapyAnastomosis, SurgicalAnastomotic LeakDrainageHumansRetrospective StudiesComplication managementLeakageRectal cancerSurgeryVacuum therapy

Identifiers

PMID37204614
PMCPMC10198851

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.