Evidence map›Paper›PMID 37204547›Full record

ArticleAnnals of biomedical engineering2023

Spatial-Temporal Oxygenation Mapping Using a Near-Infrared Optical Scanner: Towards Peripheral Vascular Imaging.

Kevin Leiva, Daniela Leizaola, Isabella Gonzalez, Valentina Dargam, Haniyeh Alirezaei, Kacie Kaile, Edwin Robledo, Joshua Hutcheson, Anuradha Godavarty

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Diabetic Foot Ulcer Imaging: An Overview and Future Directions.Journal of diabetes science and technology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kevin Leiva *Optical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, EC 2675, Miami, FL, 33174, USA.
Daniela Leizaola *Optical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, EC 2675, Miami, FL, 33174, USA.
Isabella GonzalezOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, EC 2675, Miami, FL, 33174, USA.
Valentina DargamCardiovascular Matrix Remodeling Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Haniyeh AlirezaeiOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, EC 2675, Miami, FL, 33174, USA.
Kacie KaileOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, EC 2675, Miami, FL, 33174, USA.
Edwin RobledoOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, EC 2675, Miami, FL, 33174, USA.
Joshua HutchesonCardiovascular Matrix Remodeling Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Anuradha GodavartyOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, EC 2675, Miami, FL, 33174, USA. godavart@fiu.edu.ORCID http://orcid.org/0000-0002-6094-5909
Florida International University · US

Funding

Correlating Aortic Valve Structure to Heart Sound CharacteristicF31HL154671 · NHLBI · FLORIDA INTERNATIONAL UNIVERSITY · PI DARGAM, VALENTINA · 2020 to 2023
$136k
Development of tissue oxygenation indices for acute wounds and diabetic foot ulcers using near-infrared imaging approachF31DK125153 · NIDDK · FLORIDA INTERNATIONAL UNIVERSITY · PI LEIVA, KEVIN · 2020 to 2021
$73k
CSR NIH HHS 1R01HL160740CSR NIH HHS 5U24DK115255-02CSR NIH HHS F31DK125153CSR NIH HHS F31HL154671
6 · The paper itself

Abstract

Near-infrared spectroscopy (NIRS)-based peripheral perfusion, or microcirculation, can be used to assess the severity of peripheral vascular dysfunction. A low-cost, portable non-contact near-infrared optical scanner (NIROS) was developed for spatio-temporal mapping of tissue oxygenation and perfusion in tissues. In vivo validation studies were carried out on control subjects (n = 3) to assess the ability of NIROS to measure real-time oxygenation changes in response to an occlusion paradigm on the dorsum of the hand. NIROS captured real-time tissue oxygenation changes with 95% correlation when compared to a commercial device. A feasibility peripheral imaging study was performed in a mouse model (n = 5) of chronic kidney disease (CKD) induced vascular calcification to assess differences in microcirculatory peripheral tissue oxygenation. The tissue oxygenation (in terms of oxy-, deoxy-, and total hemoglobin changes) due to the occlusion paradigm was distinctly different prior to (week-6) and after the onset of vascular calcification (week-12) in the murine tails. Future work will involve extensive studies to correlate these microcirculatory tissue oxygenation changes in the peripheral tail to the vascular calcification in the heart.

Indexed as

Vascular CalcificationVascular DiseasesAnimalsHandMiceMicrocirculationOxygenSpectroscopy, Near-InfraredUpper ExtremityOxygenHemoglobin-based concentration mapsNear-infrared spectroscopyPerfusionPeripheral vascular imagingVascular calcificationVascular occlusion test

Identifiers

PMID37204547
OpenAlexW4377093922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.