Evidence map›Paper›PMID 37204458›Full record

ArticleJournal of the American Chemical Society2023

Halide Noninnocence and Direct Photoreduction of Ni(II) Enables Coupling of Aryl Chlorides in Dual Catalytic, Carbon-Heteroatom Bond-Forming Reactions.

Cameron H Chrisman, Max Kudisch, Katherine O Puffer, Trevor K Stewart, Yisrael M L Lamb, Chern-Hooi Lim, Randolph Escobar, Pall Thordarson, Jeffrey W Johannes, Garret M Miyake

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Air-Insensitive Sulfonylation Enabled by a MOF-Supported Nickel Photocatalyst.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Photolytic activation of NiNature communications · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cameron H ChrismanDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
Max KudischDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.ORCID 0000-0002-1935-0049
Katherine O PufferDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
Trevor K StewartDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
Yisrael M L LambDepartment of Chemistry and Biochemistry, Fort Lewis College, 1000 Rim Drive, Durango, Colorado 81301, United States.ORCID 0000-0002-4888-4605
Chern-Hooi LimDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
Randolph EscobarChemistry, Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.ORCID 0000-0001-7476-7747
Pall ThordarsonSchool of Chemistry, The Australian Centre for Nanomedicine and the UNSW RNA Institute, The University of New South Wales, Sydney 2052, NSW, Australia.ORCID 0000-0002-1200-8814
Jeffrey W JohannesChemistry, Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.ORCID 0000-0001-7242-6682
Garret M MiyakeDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.ORCID 0000-0003-2451-7090

Funding

Organic Photoredox Catalysts for Synthetic Method DevelopmentR35GM144356 · NIGMS · COLORADO STATE UNIVERSITY · PI Garret Morgan Miyake · 2022 to 2026
$2.0M
Organic Polymerization Catalysis: Precision Macromolecules for Recognition in Biological SystemsR35GM119702 · NIGMS · UNIVERSITY OF COLORADO · PI MIYAKE, GARRET MORGAN · 2016 to 2020
$1.6M
Organic photoredox catalysts as sustainable and cost-effective replacement forprecious metal complexes in light-driven drug synthesisR44GM131452 · NIGMS · NEW IRIDIUM · PI LIM, CHERN-HOOI · 2020 to 2021
$1.5M
Organic photoredox catalysts as sustainable and cost-effective replacement for precious metal complexes in light-driven drug synthesisR43GM131452 · NIGMS · NEW IRIDIUM · PI LIM, CHERN-HOOI · 2019 to 2019
$225k
NIGMS NIH HHS R35 GM119702NIGMS NIH HHS R35 GM144356NIGMS NIH HHS R43 GM131452NIGMS NIH HHS R44 GM131452
6 · The paper itself

Abstract

Recent mechanistic studies of dual photoredox/Ni-catalyzed, light-driven cross-coupling reactions have found that the photocatalyst (PC) operates through either reductive quenching or energy transfer cycles. To date, reports invoking oxidative quenching cycles are comparatively rare and direct observation of such a quenching event has not been reported. However, when PCs with highly reducing excited states are used (e.g., Ir(ppy)

Identifiers

PMID37204458
PMCPMC10786213

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.