Evidence map›Paper›PMID 37204376›Full record

ReviewJournal of the American Dental Association (1939)2023

Photobiomodulation in dental extraction therapy: Postsurgical pain reduction and wound healing.

Dennis Sourvanos, Bradley Lander, Hector Sarmiento, James Carroll, Ryan D Hall, Timothy C Zhu, Joseph P Fiorellini

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American Dental Association (1939), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Photobiomodulation therapy.JADA foundational science · 2025
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dennis Sourvanos
Bradley Lander
Hector Sarmiento
James Carroll
Ryan D Hall
Timothy C Zhu
Joseph P Fiorellini

Funding

TUMOR HYPOXIA, PHOTOSENSITIZER, VASCULARITY AND PDTP01CA087971 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M, CENGEL, KEITH A · 2001 to 2019
$24.8M
NRSA Training CoreTL1TR001880 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$10.0M
Optimizing singlet oxygen dosimetry for photodynamic therapy (PDT)R01EB032821 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI HADFIELD, ROBERT HUGH, ZHU, TIMOTHY C. · 2022 to 2025
$2.4M
In situ PEDSy and light delivery platform for Intracavitory Photodynamic TherapyR01EB028778 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI POTASEK, MARY, ZHU, TIMOTHY C. · 2020 to 2023
$2.2M
Advanced Training at the Interface of Engineering and Oral-Craniofacial SciencesT90DE030854 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI Hyun Koo, Kathleen J Stebe · 2021 to 2026
$1.4M
NCATS NIH HHS TL1 TR001880NCI NIH HHS P01 CA087971NIBIB NIH HHS R01 EB028778NIBIB NIH HHS R01 EB032821NIDCR NIH HHS T90 DE030854
6 · The paper itself

Abstract

backgroundThis scoping review and analysis were designed to assess the amount of time spent delivering photobiomodulation (PBM) light therapy after dental extraction to improve postoperative pain and wound healing. TYPES OF STUDIES REVIEWED: The scoping review was performed according to the Cochrane Collaboration and Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Publications were specific for human randomized controlled clinical trials, PBM after dental extraction therapy, and related clinical outcomes. Online databases searched included PubMed, Embase, Scopus, and Web of Science. Analyses were conducted to analyze the prescribed intervals of time (seconds) per application of PBM.

resultsOf the 632 studies initially identified, 22 studies fulfilled the inclusion criteria. Postoperative pain and PBM were reported in 20 articles for 24 treatment groups, with treatment times ranging from 17 through 900 seconds and wavelengths from 550 through 1,064 nm. Clinical wound healing outcomes were reported in 6 articles for 7 groups with treatment times ranging from 30 through 120 seconds and wavelengths from 660 through 808 nm. PBM therapy was not associated with adverse events. CONCLUSIONS AND PRACTICAL IMPLICATIONS: There is future potential to integrate PBM after dental extraction therapy to improve postoperative pain and clinical wound healing. The amount of time spent delivering PBM will vary by wavelength and the type of device. Further investigation is needed to translate PBM therapy into human clinical care.

Indexed as

Low-Level Light TherapyWound HealingHumansPostoperative PainTooth ExtractiondentistryLaserlaser therapylow-level light therapyoral surgery procedurespain management, facial painphotobiomodulationtooth extraction

Identifiers

PMID37204376
PMCPMC10877507
OpenAlexW4377030486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.