Evidence map›Paper›PMID 37204239›Full record

ArticleAnalytical chemistry2023

Multiplexable and Biocomputational Virus Detection by CRISPR-Cas9-Mediated Strand Displacement.

Rosa Márquez-Costa, Roser Montagud-Martínez, María-Carmen Marqués, Eliseo Albert, David Navarro, José-Antonio Daròs, Raúl Ruiz, Guillermo Rodrigo

Open access · hybridAbstract read
In one paragraph

Article in Analytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rosa Márquez-CostaInstitute for Integrative Systems Biology (I2SysBio), CSIC - University of Valencia, 46980 Paterna, Spain.ORCID 0000-0001-9956-0873
Roser Montagud-MartínezInstitute for Integrative Systems Biology (I2SysBio), CSIC - University of Valencia, 46980 Paterna, Spain.
María-Carmen MarquésInstitute for Integrative Systems Biology (I2SysBio), CSIC - University of Valencia, 46980 Paterna, Spain.
Eliseo AlbertMicrobiology Service, Clinic University Hospital, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.
David NavarroMicrobiology Service, Clinic University Hospital, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.
José-Antonio DaròsInstituto de Biología Molecular y Celular de Plantas (IBMCP), CSIC - Universitat Politècnica de València, 46022 Valencia, Spain.ORCID 0000-0002-6535-2889
Raúl RuizInstitute for Integrative Systems Biology (I2SysBio), CSIC - University of Valencia, 46980 Paterna, Spain.
Guillermo RodrigoInstitute for Integrative Systems Biology (I2SysBio), CSIC - University of Valencia, 46980 Paterna, Spain.ORCID 0000-0002-1871-9617
Universitat de València · ESINCLIVA Health Research Institute · ESInstituto de Biología Molecular y Celular de Plantas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent disease outbreaks caused by different viruses, including the novel respiratory virus SARS-CoV-2, are challenging our society at a global scale; so versatile virus detection methods would enable a calculated and faster response. Here, we present a novel nucleic acid detection strategy based on CRISPR-Cas9, whose mode of action relies on strand displacement rather than on collateral catalysis, using the

Indexed as

COVID-19CRISPR-Cas SystemsDNAHumansSARS-CoV-2DNA

Identifiers

PMID37204239
PMCPMC10255568
OpenAlexW4377093282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.