Evidence map›Paper›PMID 37202924›Full record

ArticleACS biomaterials science & engineering2023

Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol-Gel Coating.

Andreia Cerqueira, Francisco Romero-Gavilán, Heike Helmholz, Mikel Azkargorta, Félix Elortza, Mariló Gurruchaga, Isabel Goñi, Regine Willumeit-Römer, Julio Suay

Open access · hybridAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Andreia CerqueiraDepartment of Industrial Systems Engineering and Design, Universitat Jaume I, Av. Vicent Sos Baynat s/n, 12071 Castellón de la Plana, Spain.ORCID 0000-0001-9281-069X
Francisco Romero-GavilánDepartment of Industrial Systems Engineering and Design, Universitat Jaume I, Av. Vicent Sos Baynat s/n, 12071 Castellón de la Plana, Spain.ORCID 0000-0001-8300-7248
Heike HelmholzHelmholtz-Zentrum Hereon Institute of Metallic Biomaterials, Max-Planck-St.1, Geesthacht D-21502, Germany.ORCID 0000-0001-6457-3607
Mikel AzkargortaProteomics Platform, Basque Research and Technology Alliance (BRTA), CIBERehd, Bizkaia Science and Technology Park, CIC bioGUNE, 48160 Derio, Spain.
Félix ElortzaProteomics Platform, Basque Research and Technology Alliance (BRTA), CIBERehd, Bizkaia Science and Technology Park, CIC bioGUNE, 48160 Derio, Spain.
Mariló GurruchagaDepartment of Science and Technology of Polymers, University of the Basque Country, P. M. de Lardizábal, 3, 20018 San Sebastián, Spain.
Isabel GoñiDepartment of Science and Technology of Polymers, University of the Basque Country, P. M. de Lardizábal, 3, 20018 San Sebastián, Spain.
Regine Willumeit-RömerHelmholtz-Zentrum Hereon Institute of Metallic Biomaterials, Max-Planck-St.1, Geesthacht D-21502, Germany.
Julio SuayDepartment of Industrial Systems Engineering and Design, Universitat Jaume I, Av. Vicent Sos Baynat s/n, 12071 Castellón de la Plana, Spain.
Universitat Jaume I · ESEuskadiko Parke Teknologikoa · ESHelmholtz-Zentrum Hereon · DEUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused on monocultures, even though co-cultures model better the natural tissue. For instance, human mesenchymal stem cells (MSCs) modulate immune responses and promote bone repair through interaction with other cell types. Here, label-free liquid chromatography tandem mass spectroscopy proteomic methods were applied for the first time to characterize HUCPV (MSC) and CD14

Indexed as

Mesenchymal Stem CellsMonocytesCoculture TechniquesGlutathione TransferaseHumansIntegrinsProteomicsSilicon DioxideGlutathione TransferaseGSTO1 protein, humanIntegrinsSilicon Dioxidebiomaterialsco-culturesosteoimmunologyproteomicssol−gel coatings

Identifiers

PMID37202924
PMCPMC10265575
OpenAlexW4377092872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.