Evidence map›Paper›PMID 37202831›Full record

ArticleTranslational behavioral medicine2023

Accelerating Colorectal Cancer Screening and Follow-up through Implementation Science (ACCSIS) in Appalachia: protocol for a group randomized, delayed intervention trial.

Electra D Paskett, Aaron J Kruse-Diehr, Jill M Oliveri, Robin C Vanderpool, Darrell M Gray, Michael L Pennell, Bin Huang, Gregory S Young, Darla Fickle, Mark Cromo and 13 more

Open access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Translational behavioral medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 3 institutions in 1 country.

Electra D PaskettThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0002-8247-8299
Aaron J Kruse-DiehrUniversity of Kentucky College of Medicine, Department of Family and Community Medicine, Lexington, KY, USA.ORCID 0000-0003-2952-0248
Jill M OliveriThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0002-6222-8217
Robin C VanderpoolUniversity of Kentucky College of Public Health, Department of Health, Behavior and Society, Lexington, KY, USA.ORCID 0000-0001-9995-4485
Darrell M GrayThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0003-2506-3465
Michael L PennellThe Ohio State University College of Public Health, Division of Biostatistics, Columbus, OH, USA.ORCID 0000-0002-2602-3126
Bin HuangUniversity of Kentucky Markey Cancer Center, Division of Biostatistics, Biostatistics and Bioinformatics Shared Resource Facility, Lexington, KY, USA.ORCID 0000-0002-9075-1531
Gregory S YoungCollege of Medicine, Department of Biomedical Informatics.
Darla FickleThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Mark CromoUniversity of Kentucky College of Medicine, Department of Internal Medicine, Lexington, KY, USA.ORCID 0000-0002-5699-3844
Mira L KatzThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Paul L ReiterThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0001-8252-2600
Melinda RogersUniversity of Kentucky Markey Cancer Center, Community Impact Office, Lexington, KY, USA.
David A GrossNortheast Kentucky Area Health Education Center, Morehead, KY, USA.
Vickie FairchildNortheast Kentucky Area Health Education Center, Morehead, KY, USA.
Wendy XuThe Ohio State University College of Public Health, Division of Health Services Management and Policy, Columbus, OH, USA.
Angela CarmanUniversity of Kentucky Markey Cancer Center, Cancer Prevention and Control Research Program, Lexington, KY, USA.
Jean M WalunisThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Ann Scheck McAlearneyThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0001-9107-5419
Timothy R HuertaThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0002-9978-3564
Saurabh RahurkarCollege of Medicine, Department of Biomedical Informatics.ORCID 0000-0001-8597-3087
Erika BiedermanThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0001-6221-5806
Mark DignanUniversity of Kentucky College of Medicine, Department of Internal Medicine, Lexington, KY, USA.
The Ohio State University · USUniversity of Kentucky · USKentucky Department of Education · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers · 2013 to 2026
$38.3M
(ACCSIS) Accelerating Colorectal Cancer Screening through Implementation Science in AppalachiaUH3CA233282 · NCI · UNIVERSITY OF KENTUCKY · PI DIGNAN, MARK B, PASKETT, ELECTRA D. · 2019 to 2022
$4.6M
Training Program For Cancer Prevention and ControlT32CA229114 · NCI · OHIO STATE UNIVERSITY · PI Chyke Abadama Doubeni, Peter G. Shields · 2018 to 2026
$2.0M
NCI NIH HHS 4UH3CA233282-02NCI NIH HHS P30 CA016058NCI NIH HHS P30 CA177558NCI NIH HHS T32 CA229114NCI NIH HHS UH3 CA233282
6 · The paper itself

Abstract

Appalachian regions of Kentucky and Ohio are hotspots for colorectal cancer (CRC) mortality in the USA. Screening reduces CRC incidence and mortality; however, screening uptake is needed, especially in these underserved geographic areas. Implementation science offers strategies to address this challenge. The aim of the current study was to conduct multi-site, transdisciplinary research to evaluate and improve CRC screening processes using implementation science strategies. The study consists of two phases (Planning and Implementation). In the Planning Phase, a multilevel assessment of 12 health centers (HC) (one HC from each of the 12 Appalachian counties) was conducted by interviewing key informants, creating community profiles, identifying HC and community champions, and performing HC data inventories. Two designated pilot HCs chose CRC evidence-based interventions to adapt and implement at each level (i.e., patient, provider, HC, and community) with evaluation relative to two matched control HCs. During the Implementation Phase, study staff will repeat the rollout process in HC and community settings in a randomized, staggered fashion in the remaining eight counties/HCs. Evaluation will include analyses of electronic health record data and provider and county surveys. Rural HCs have been reluctant to participate in research because of concerns about capacity; however, this project should demonstrate that research does not need to be burdensome and can adapt to local needs and HC abilities. If effective, this approach could be disseminated to HC and community partners throughout Appalachia to encourage the uptake of effective interventions to reduce the burden of CRC.

Indexed as

Colorectal NeoplasmsImplementation ScienceAppalachian RegionEarly Detection of CancerFollow-Up StudiesHumansMass ScreeningRandomized Controlled Trials as TopicAppalachiaColorectal cancerGroup randomized trialImplementation strategyMultilevel interventions

Identifiers

PMID37202831
PMCPMC10538475
OpenAlexW4377093554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.