Evidence map›Paper›PMID 37202827›Full record

ArticleBMC research notes2023

In vitro anti-Toxoplasma gondii activity of Ganoderma lucidum extracts.

Mohammad Ahmadi, Mahboobeh Salimi, Mehrzad Saraei, Niloofar Salavati Nezhad, Amir Javadi, Faezeh Mohammadi, Peyman Heydarian, Ehsan Ali, Elham Hajialilo

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Article in BMC research notes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Exploring the health benefits ofFrontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammad AhmadiStudent Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
Mahboobeh SalimiDepartment of medical parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran.
Mehrzad SaraeiMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Niloofar Salavati NezhadDepartment of medicine Biotechnology, Faculty of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Amir JavadiDepartment of Community Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Faezeh MohammadiMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Peyman HeydarianMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Ehsan AliDepartment of Pharmacology, Qazvin University of Medical Sciences, Qazvin, Iran.
Elham HajialiloMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. e.hajialilo@gmail.com.ORCID http://orcid.org/0000-0003-2159-4066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGanoderma extracts have the potential to be used as anti-cancer, anti-inflammatory, immunomodulator, and antimicrobial agents, as evaluated in numerous studies. This study was aimed to determine the lethal and inhibitory effects of aqueous, hydroalcoholic, and alcoholic extracts of Ganoderma lucidum on Toxoplasma gondii RH strain tachyzoites, in vitro.

resultsAll three types of extracts showed toxoplasmacidal effects. The highest percentage of mortality was related to hydroalcoholic extract. The EC50 of Ganoderma extracts for tachyzoites were 76.32, 3.274, and 40.18 for aqueous, hydroalcoholic and alcoholic extracts, respectively. The selectivity index obtained for hydroalcoholic extract was 71.22, showing the highest activity compared to other extracts. According to our findings, the hydroalcoholic part was the most effective substance among the extracts. This basic study showed obvious anti-toxoplasma effect of Ganoderma lucidum extracts. These extracts can be used as candidates for further in-depth and comprehensive studies especially In vivo experiments to prevent toxoplasmosis.

Indexed as

Anti-Infective AgentsGanodermaReishiToxoplasmaToxoplasmosisAnti-Inflammatory AgentsHumansPlant ExtractsAnti-Infective AgentsAnti-Inflammatory AgentsPlant ExtractsGanoderma lucidumIn vitroIranToxoplasma gondii

Identifiers

PMID37202827
PMCPMC10197208

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.