Evidence map›Paper›PMID 37202824›Full record

ArticleInternational journal of retina and vitreous2023

Macular vascular features of different types of diabetic macular edema using ocular coherence tomography angiography- a comparative study.

Ghada A Nassar, Ibrahim M Maqboul, Ayman Gehad El-Nahry, Lameece Moustafa Hassan, Ahmed B Shalash

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Article in International journal of retina and vitreous, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ghada A NassarCairo University, 3 Road 217, Degla Maadi, Cairo, Egypt.
Ibrahim M MaqboulCairo University, 3 Road 217, Degla Maadi, Cairo, Egypt.
Ayman Gehad El-NahryCairo University, 3 Road 217, Degla Maadi, Cairo, Egypt.
Lameece Moustafa HassanCairo University, 3 Road 217, Degla Maadi, Cairo, Egypt. lameecemoustafa@kasralainy.edu.eg.ORCID http://orcid.org/0000-0002-8900-7107
Ahmed B ShalashCairo University, 3 Road 217, Degla Maadi, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the microvascular features of different subtypes of diabetic macular edema (DME) by optical coherence tomography angiography (OCTA).

methodsA cross-sectional study including treatment-naive patients with DME. Eyes were divided according to optical coherence tomography determined morphology into two groups: cystoid macular edema (CME) and diffuse retinal thickening (DRT), with further subdivision according to the presence of subretinal fluid. All patients underwent 3 × 3 and 6 × 6 mm OCTA scans of the macula to compare the foveal avascular zone (FAZ) area, vascular density (VD) of the superficial (SCP) and deep (DCP) capillary plexus and choriocapillaris flow (CF). Laboratory findings (HbA1C and triglyceride levels) were also correlated with the OCTA findings.

resultsThe study included 52 eyes, 27 had CME and 25 had DRT. There were no significant differences between the VD of the SCP (p = 0.684) and DCP (p = 0.437), FAZ of SCP (p = 0.574), FAZ of DCP (p = 0.563) and CF (p = 0.311). Linear regression analysis revealed that DME morphology was the strongest predictor for BCVA. Other significant predictors included HbA1C and triglyceride levels.

conclusionThe morphology of DME, irrespective of SRF, was most significantly correlated with BCVA in treatment-naive patients and CME subtype could be an independent predictor of poor BCVA in patients with DME.

Indexed as

ChoriocapillarisCystoid macular edemaDiabetic macular edemaDiffuse retinal thickeningFoveal avascular zoneNeurosensory detachmentOptical coherence tomography angiography

Identifiers

PMID37202824
PMCPMC10197445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.